Which explanation best describes the most common cause of duodenal ulcers?
Fewer numbers of parietal cells in the gastric mucosa
Helicobacter pylori infection
Slowed gastric emptying
Frequent use of acetaminophen
The Correct Answer is B
Choice A reason: Fewer numbers of parietal cells in the gastric mucosa is not the best explanation because it is a condition that affects the production of gastric acid, not the development of duodenal ulcers. Parietal cells are the cells that secrete hydrochloric acid and intrinsic factor in the stomach. Hydrochloric acid helps to digest food and kill bacteria, while intrinsic factor helps to absorb vitamin B12. Fewer numbers of parietal cells can cause hypochlorhydria, which is a low level of gastric acid, or pernicious anemia, which is a deficiency of vitamin B12. Hypochlorhydria can increase the risk of bacterial overgrowth and infections, while pernicious anemia can cause symptoms such as fatigue, weakness, and neurological problems.
Choice B reason: Helicobacter pylori infection is the best explanation because it is the most common cause of duodenal ulcers, which are sores that form in the lining of the first part of the small intestine, called the duodenum. Helicobacter pylori is a type of bacteria that can survive in the acidic environment of the stomach and the duodenum. It can damage the protective layer of mucus that covers the lining of the digestive tract, exposing it to the gastric acid and causing inflammation and ulceration. Helicobacter pylori infection can also increase the production of gastrin, which is a hormone that stimulates the secretion of gastric acid, and decrease the production of somatostatin, which is a hormone that inhibits the secretion of gastric acid.
Choice C reason: Slowed gastric emptying is not the best explanation because it is a condition that affects the movement of food from the stomach to the small intestine, not the development of duodenal ulcers. Gastric emptying is the process of passing the food that has been partially digested in the stomach to the duodenum, where it is further broken down and absorbed. Slowed gastric emptying can be caused by various factors, such as diabetes, medications, or nerve damage, and can result in symptoms such as nausea, vomiting, bloating, or fullness.
Choice D reason: Frequent use of acetaminophen is not the best explanation because it is a factor that affects the development of gastric ulcers, not duodenal ulcers. Acetaminophen is a type of medication that is used to relieve pain and fever. It can cause gastric ulcers by inhibiting the synthesis of prostaglandins, which are substances that protect the lining of the stomach from the gastric acid and promote healing. Acetaminophen can also cause liver damage if taken in high doses or for a long time.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Prostaglandins are inflammatory mediators that are derived from arachidonic acid. They are involved in both the early and late phases of type 1 hypersensitivity response, but they do not cause immediate bronchoconstriction and vasodilation. They mainly cause pain, fever, and inflammation.
Choice B reason: Histamine is an inflammatory mediator that is stored in mast cells and basophils. It is released during the early phase of type 1 hypersensitivity response, which occurs within minutes of exposure to an allergen. It causes immediate bronchoconstriction and vasodilation, as well as increased vascular permeability, mucus secretion, and itching.
Choice C reason: Leukotrienes are inflammatory mediators that are derived from arachidonic acid. They are involved in the late phase of type 1 hypersensitivity response, which occurs several hours after exposure to an allergen. They cause sustained bronchoconstriction and inflammation, as well as increased mucus production and airway edema.
Choice D reason: Bradykinin is an inflammatory mediator that is formed from plasma proteins. It is not directly involved in type 1 hypersensitivity response, but it may be activated by the complement system, which is part of the innate immune system. It causes vasodilation, increased vascular permeability, and pain.
Correct Answer is D
Explanation
Choice A reason: The thyroid gland is cancerous is not a correct description of a goiter. A goiter is a non-specific term that refers to any enlargement of the thyroid gland, which may have various causes and may or may not be associated with thyroid cancer.
Choice B reason: The client has a low serum calcium level is not a correct description of a goiter. A low serum calcium level is a sign of hypoparathyroidism, which is a condition that affects the parathyroid glands, not the thyroid gland. The parathyroid glands are located behind the thyroid gland and regulate the calcium and phosphorus levels in the blood.
Choice C reason: The thyroid gland has been surgically removed is not a correct description of a goiter. A goiter is a condition that involves the presence of an enlarged thyroid gland, not the absence of it. A surgical removal of the thyroid gland is called a thyroidectomy, which may be done for various reasons such as thyroid cancer, hyperthyroidism, or large goiters.
Choice D reason: The thyroid gland is enlarged is the best description of a goiter. A goiter is a condition that involves the enlargement of the thyroid gland, which may be due to iodine deficiency, autoimmune disease, inflammation, infection, benign nodules, or thyroid hormone imbalance. A goiter may cause symptoms such as difficulty swallowing, breathing, or speaking, hoarseness, cough, or neck discomfort.
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