Which instruction is most appropriate for a client who is prescribed pancrelipase (Cotazym)?

Increase dosing with a large meal

Take the medication at least 2 hours prior to meals

Take the medication with meals

Decrease fluid intake

Answer and Explanation

The Correct Answer is C

A) Increase dosing with a large meal:
Increasing the dosing with a large meal may not be appropriate as it could lead to overdosing and potential side effects. The dosage of pancrelipase should be determined by the healthcare provider based on the individual's needs and response to treatment.

B) Take the medication at least 2 hours prior to meals:
Taking the medication prior to meals may not be effective as the enzymes will not be available when food is consumed, which defeats the purpose of enzyme replacement therapy. The enzymes need to be present simultaneously with the food to aid in digestion.

C) Take the medication with meals.
Pancrelipase, such as Cotazym, is a pancreatic enzyme replacement therapy used to aid in the digestion of fats, proteins, and carbohydrates in individuals with pancreatic insufficiency. Taking the medication with meals is crucial because it helps to ensure that the enzymes are available to aid in the digestion of food. Without proper enzyme supplementation during meals, individuals with pancreatic insufficiency may experience malabsorption, leading to nutritional deficiencies and gastrointestinal symptoms.

D) Decrease fluid intake:
Decreasing fluid intake is not appropriate as it could lead to dehydration and may not have any significant impact on the efficacy of pancrelipase. In fact, adequate fluid intake is important for digestion and overall health.

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Correct Answer is D

Explanation

A) H2-receptor blockers:
H2-receptor blockers, such as ranitidine and famotidine, are used to reduce the production of stomach acid. While they can provide symptomatic relief for ulcers by reducing acid secretion, they do not directly treat the underlying cause of the ulcer, which is the H. pylori infection.

B) Antacids:
Antacids are medications that neutralize stomach acid and can provide temporary relief from ulcer symptoms such as pain and discomfort. However, they do not eradicate the H. pylori bacteria or address the root cause of the ulcer. Antacids only provide symptomatic relief rather than treating the infection.

C) Proton-pump inhibitors:
Proton-pump inhibitors (PPIs), such as omeprazole and pantoprazole, are potent acid-suppressing medications that are commonly used to treat ulcers and gastroesophageal reflux disease (GERD). While they can help in ulcer healing by reducing acid secretion and providing symptomatic relief, they are not effective in eradicating H. pylori infection. PPIs are often used in combination with antibiotics for H. pylori eradication therapy, but they are not the primary treatment on their own.

D) Antibiotics.
H. pylori (Helicobacter pylori) is a bacteria that commonly infects the stomach lining and is a major cause of gastric and duodenal ulcers. Antibiotics are the primary treatment for H. pylori infection. The antibiotics kill the bacteria, allowing the ulcer to heal. Common antibiotics used to treat H. pylori include amoxicillin, clarithromycin, metronidazole, and tetracycline.

Correct Answer is ["10"]

Explanation

To administer the correct dose of valproic acid, which is 500 mg, when the available oral solution concentration is 250 mg per 5 mL, the nurse needs to calculate the volume of the solution required.

The calculation is as follows: (500 mg) / (250 mg/5 mL) = 2 x 5 mL = 10 mL.

Therefore, the nurse should administer 10 mL of the valproic acid oral solution to deliver a dose of 500 mg.

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Which instruction is most appropriate for a client who is prescribed pancrelipase (Cotazym)?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

An ulcer caused by H. pylori can be successfully treated with which classification of drugs?

Correct Answer is D

Explanation

A nurse is preparing to administer valproic acid 500 mg PO. Available is valproic acid oral solution 250 mg/5 mL. How many mL should they administer? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Correct Answer is ["10"]

Explanation

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