A nurse is preparing to administer diphenhydramine to a client who is to receive a blood transfusion. The nurse should explain that the purpose diphenhydramine is to prevent which of the following manifestations of a transfusion reaction?

A) Cardiogenic shock:
Cardiogenic shock occurs when the heart is unable to pump enough blood to meet the body's needs, often due to myocardial infarction (heart attack) or other conditions affecting the heart's function. The client's history of a recent infection does not align with the etiology of cardiogenic shock.

B) Neurogenic shock:
Neurogenic shock occurs due to dysfunction of the autonomic nervous system, typically as a result of spinal cord injury or severe brain injury. It is characterized by widespread vasodilation and bradycardia. The client's history of a recent infection does not align with the etiology of neurogenic shock.

C) Hypovolemic shock:
Hypovolemic shock occurs due to a significant loss of blood volume, such as from trauma, hemorrhage, or dehydration. While infection can lead to fluid loss and dehydration in some cases, the client's history of a recent infection suggests a different etiology, specifically septic shock, which is driven by the systemic inflammatory response to infection.

D) Septic shock.
Septic shock is a type of distributive shock caused by a systemic response to infection. It occurs when an infection triggers a widespread inflammatory response, leading to vasodilation, increased capillary permeability, fluid loss from the bloodstream, and impaired tissue perfusion. The client's history of a recent infection suggests that the shock may be septic in nature.

A. The inside surface of the lungs is small, and the dose is concentrated in that area: Inhalation medications are delivered directly to the lungs, where they are rapidly absorbed due to the small surface area and the close proximity of the medication to the lung tissue.

B. There is a large surface area inside the lungs: The lungs have a large surface area for gas exchange, allowing for efficient absorption of inhaled medications into the bloodstream.

C. Inhaled medications are given at very high doses: Inhaled medications are typically given at therapeutic doses appropriate for the patient's condition. While they may be given in higher doses compared to oral medications in some cases, the dosage is carefully adjusted based on factors such as the patient's age, weight, and severity of the condition.

D. Inhaled medications are given with food: Inhaled medications are typically administered separately from meals. Food can interfere with the absorption of inhaled medications and may affect their effectiveness.
E. There is a rich blood supply to the lungs: The lungs have a rich network of blood vessels, known as pulmonary capillaries, which allows for rapid absorption of inhaled medications into the bloodstream.