Which laboratory finding indicates the resolution of a patient's acute pancreatitis?

Choice A rationale

An increasing hemoglobin level does not indicate the resolution of acute pancreatitis. Hemoglobin levels can fluctuate due to various factors, including hydration status and blood loss, but are not directly related to the resolution of pancreatitis.

Choice B rationale

During an episode of acute pancreatitis, serum concentrations of amylase and lipase rise significantly, often within hours of pancreatic injury. These elevated enzyme levels are key components in diagnosing the condition. As the inflammation subsides and the pancreas begins to heal, the levels of these enzymes typically decrease, returning to normal ranges. Therefore, a declining serum amylase level suggests that the acute inflammatory process is resolving.

Choice C rationale

Serum bilirubin levels are indicative of liver function and bile metabolism. Elevated bilirubin may occur if pancreatitis leads to bile duct obstruction or liver involvement. However, a decrease in bilirubin levels addresses biliary system recovery rather than directly reflecting pancreatic inflammation resolution.

Choice D rationale

An increasing serum alkaline phosphatase level is generally associated with bile duct obstruction or bone disease and does not indicate the resolution of acute pancreatitis. This enzyme is found in several tissues throughout the body, including the liver and bones.

Choice A rationale
Diarrhea is a common symptom in both ulcerative colitis (UC) and Crohn's disease, often presenting with urgency and frequency.

Choice B rationale
Lesions that penetrate the intestine are more characteristic of Crohn's disease, which can affect any layer of the intestinal wall and any part of the gastrointestinal tract.

Choice C rationale
Strictures are more common in Crohn's disease due to its transmural inflammatory nature, which can lead to fibrosis and narrowing of the intestines¹.

Choice D rationale
UC is restricted to the colon and often involves the rectum, but Crohn's disease can affect any part of the gastrointestinal tract from the mouth to the anus and is not restricted to the rectum¹.