Which of following best described the mechanism of action for Donepezil (Aricept)?
Prevent breakdown of acetylcholinesterase by inhibiting the action of acetylcholine
Prevent breakdown of acetylcholine by inhibiting the action of acetylcholinesterase
Promote breakdown of acetylcholine by inhibiting the action of acetylcholinesterase
Promote breakdown of acetylcholinesterase by inhibiting the action of acetylcholine
The Correct Answer is B
A. Prevent breakdown of acetylcholinesterase by inhibiting the action of acetylcholine is incorrect because the mechanism of Donepezil (Aricept) involves inhibiting acetylcholinesterase, not acetylcholine itself. The goal is to increase the levels of acetylcholine in the brain by preventing its breakdown.
B. Prevent breakdown of acetylcholine by inhibiting the action of acetylcholinesterase is the correct mechanism. Donepezil is a cholinesterase inhibitor. By inhibiting acetylcholinesterase (the enzyme that breaks down acetylcholine), Donepezil increases the amount of acetylcholine available to stimulate receptors in the brain, which helps improve symptoms of Alzheimer's disease.
C. Promote breakdown of acetylcholine by inhibiting the action of acetylcholinesterase is incorrect because Donepezil prevents the breakdown of acetylcholine, not promotes it.
D. Promote breakdown of acetylcholinesterase by inhibiting the action of acetylcholine is also incorrect. The purpose of Donepezil is to prevent the breakdown of acetylcholine, not to break down acetylcholinesterase itself.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Physical or chemical means or device that restricts client's freedom to and ability to move about is the most accurate definition of restraint. This includes any method or device used to prevent a patient from moving freely, such as physical devices (like straps or handcuffs) or chemical restraints (medications used to sedate or calm the patient).
B. The involuntary confinement of a patient alone in a room or area from which the patient is physically prevented from leaving refers to seclusion, not restraints. Seclusion is a form of isolation, often used when a patient is a danger to themselves or others, but it is distinct from restraints.
C. Pharmacological interventions for management of acute behavioral emergencies refers to the use of medication, but this is not specifically a restraint. Restraints involve preventing movement or controlling behavior through either physical or chemical means, but this definition is more about the use of medication in emergencies rather than restricting movement.
D. Safety measures to prevent a threatened or attempted suicide or some serious bodily injury describes precautionary measures rather than the definition of restraint itself. Restraints are about restricting movement, not necessarily about preventing injury or harm directly.
Correct Answer is A
Explanation
A. Workplace bullying includes repeated, unreasonable actions directed toward an employee intended to intimidate, degrade, or undermine. In this scenario, the charge nurse dismisses the new grad’s valid concerns and gives a difficult assignment without support, contributing to an unsafe and unsupportive environment — classic signs of bullying.
B. Workplace violence typically refers to physical acts of aggression or threats. This situation, while harmful, does not involve violence.
C. Ageism refers to discrimination based on a person’s age, which is not a factor in this scenario.
D. While new grads are expected to learn and grow into their roles, being overwhelmed with unsafe assignments and receiving no support is not normal or acceptable.
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