Which of following best described the mechanism of action for Donepezil (Aricept)?

Prevent breakdown of acetylcholinesterase by inhibiting the action of acetylcholine

Prevent breakdown of acetylcholine by inhibiting the action of acetylcholinesterase

Promote breakdown of acetylcholine by inhibiting the action of acetylcholinesterase

Promote breakdown of acetylcholinesterase by inhibiting the action of acetylcholine

Answer and Explanation

The Correct Answer is B

A. Prevent breakdown of acetylcholinesterase by inhibiting the action of acetylcholine is incorrect because the mechanism of Donepezil (Aricept) involves inhibiting acetylcholinesterase, not acetylcholine itself. The goal is to increase the levels of acetylcholine in the brain by preventing its breakdown.
B. Prevent breakdown of acetylcholine by inhibiting the action of acetylcholinesterase is the correct mechanism. Donepezil is a cholinesterase inhibitor. By inhibiting acetylcholinesterase (the enzyme that breaks down acetylcholine), Donepezil increases the amount of acetylcholine available to stimulate receptors in the brain, which helps improve symptoms of Alzheimer's disease.
C. Promote breakdown of acetylcholine by inhibiting the action of acetylcholinesterase is incorrect because Donepezil prevents the breakdown of acetylcholine, not promotes it.
D. Promote breakdown of acetylcholinesterase by inhibiting the action of acetylcholine is also incorrect. The purpose of Donepezil is to prevent the breakdown of acetylcholine, not to break down acetylcholinesterase itself.

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Correct Answer is B

Explanation

A. Confusion is a common symptom of delirium tremens (DTs). It is one of the hallmark signs of alcohol withdrawal delirium, characterized by altered mental status and disorientation.
B. Hypertension is not typically a defining symptom of delirium tremens, although it can sometimes occur in the broader context of withdrawal. However, it is not a primary feature of DTs. The more characteristic symptoms are related to neurological and autonomic disturbances, such as tremors and seizures.
C. Seizures are a well-known symptom of delirium tremens. Withdrawal from alcohol, especially after prolonged heavy use, can lead to seizures, which are a significant concern in DTs.
D. Severe tremors (or shakes) are a hallmark symptom of delirium tremens. These tremors are usually very pronounced and can affect the hands, face, or whole body.

A. Methadone B. Lorazepam C. Subutex D. Naltrexone

Correct Answer is B

Explanation

A. Methadone is commonly used in the treatment of opiate dependence. It is a long-acting opioid agonist that helps reduce withdrawal symptoms and cravings, allowing patients to stabilize and recover without experiencing the highs and lows of illicit drug use.
B. Lorazepam is a benzodiazepine used to treat anxiety, insomnia, and sometimes alcohol withdrawal. It is not used for opiate dependence and can actually be dangerous if combined with opioids, as it can increase the risk of respiratory depression and overdose.
C. Subutex is a brand name for buprenorphine, which is used to treat opioid dependence. It is a partial opioid agonist that helps reduce cravings and withdrawal symptoms without producing the high associated with full opioid agonists.
D. Naltrexone is used to treat both opioid and alcohol dependence. It is an opioid antagonist that works by blocking the effects of opioids, helping to prevent relapse in individuals who have already detoxified from opioids.

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Which of following best described the mechanism of action for Donepezil (Aricept)?

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Naxlex Comprehensive Predictor Exams

All of the following are symptoms of delirium tremens except

Correct Answer is B

Explanation

All of the following are used for opiate dependence except

Correct Answer is B

Explanation

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