Which of the following is a severe adverse reaction associated with aminoglycoside therapy?
Rash
Nausea and vomiting
Ototoxicity
Headache
The Correct Answer is C
A. Rash is generally a mild adverse effect and does not indicate a severe reaction.
B. Nausea and vomiting are common side effects but not classified as severe reactions.
C. Ototoxicity is a severe adverse reaction associated with aminoglycoside therapy, potentially leading to hearing loss and balance issues. Monitoring for this side effect is crucial during treatment.
D. Headache can occur but is not considered a severe adverse reaction compared to ototoxicity.
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Related Questions
Correct Answer is C
Explanation
A. Inhibition of protein synthesis is the mechanism of action for other classes of antibiotics, such as tetracyclines and macrolides.
B. Inhibition of DNA replication is characteristic of fluoroquinolones.
C. Cephalosporins work by inhibiting cell wall synthesis, leading to bacterial lysis and death. This mechanism is critical for their effectiveness against a wide range of bacterial infections.
D. Inhibition of folic acid synthesis is primarily associated with sulfonamides.
Correct Answer is D
Explanation
A. This option describes drug-drug interactions, which are part of pharmacodynamics rather than pharmacokinetics.
B. The development and manufacturing of drugs pertain more to pharmaceutical sciences than pharmacokinetics.
C. Prescribing and administering drugs are related to pharmacotherapy but do not encompass the full scope of pharmacokinetics.
D. Pharmacokinetics is defined as the study of how drugs are absorbed, distributed, metabolized, and excreted by the body, providing insights into the drug's action and efficacy.
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