Which of the following is a severe adverse reaction associated with aminoglycoside therapy?
Rash
Nausea and vomiting
Ototoxicity
Headache
The Correct Answer is C
A. Rash is generally a mild adverse effect and does not indicate a severe reaction.
B. Nausea and vomiting are common side effects but not classified as severe reactions.
C. Ototoxicity is a severe adverse reaction associated with aminoglycoside therapy, potentially leading to hearing loss and balance issues. Monitoring for this side effect is crucial during treatment.
D. Headache can occur but is not considered a severe adverse reaction compared to ototoxicity.
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Related Questions
Correct Answer is D
Explanation
A. Aminoglycosides are ineffective against viral infections, as they target bacterial pathogens.
B. While some aminoglycosides may have activity against certain Gram-positive bacteria, they are mainly used for Gram-negative infections.
C. Fungal infections require antifungal agents, not aminoglycosides.
D. Aminoglycosides are primarily effective against Gram-negative bacteria, making them valuable in treating serious infections caused by these organisms.
Correct Answer is B
Explanation
A. This option incorrectly describes a placebo, which is not related to the concept of a prototype drug.
B. A prototype drug is defined as a medication that is considered the standard or model for a particular drug class or category, serving as a reference for the development of other drugs in that class.
C. Prototype drugs can be available in both brand and generic forms; this option is not accurate.
D. Prototype drugs are not limited to pediatric use and can be prescribed for patients of all ages.
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