Which of the following is a severe adverse reaction associated with aminoglycoside therapy?
Rash
Nausea and vomiting
Ototoxicity
Headache
The Correct Answer is C
A. Rash is generally a mild adverse effect and does not indicate a severe reaction.
B. Nausea and vomiting are common side effects but not classified as severe reactions.
C. Ototoxicity is a severe adverse reaction associated with aminoglycoside therapy, potentially leading to hearing loss and balance issues. Monitoring for this side effect is crucial during treatment.
D. Headache can occur but is not considered a severe adverse reaction compared to ototoxicity.
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Related Questions
Correct Answer is C
Explanation
A. This option refers to pharmaceutical formulation, not pharmacodynamics.
B. This description pertains to pharmacokinetics, which involves drug absorption, distribution, metabolism, and elimination.
C. Pharmacodynamics is defined as the study of how drugs interact with specific drug receptors to produce a physiological response, explaining the effects of drugs on the body.
D. This option relates to drug development and testing rather than the specific interactions of drugs within the body.
Correct Answer is B
Explanation
A. This option misrepresents critical concentration; it focuses on absorption rather than therapeutic efficacy.
B. The critical concentration refers to the minimum concentration of a medication in the blood needed to achieve the desired therapeutic effect. This concentration is essential to ensure that the medication is effective in treating the condition.
C. While the maximum concentration can relate to safety, critical concentration specifically concerns the minimum required for effectiveness.
D. This choice suggests an optimal concentration, which is different from the minimum concentration needed to achieve therapeutic effects.
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