Which of the following is an indirect effect of PTH?
Activating vitamin D
Increasing calcium reabsorption in the kidney
Increasing calcium absorption in the intestines
Increasing osteoclast activity
The Correct Answer is C
a) Activating vitamin D: This is a direct effect of PTH-PTH stimulates the activation of vitamin D (specifically, conversion to calcitriol) in the kidneys.
b) Increasing calcium reabsorption in the kidney: Also a direct effect-PTH acts on renal tubules to increase reabsorption of calcium.
c) Increasing calcium absorption in the intestines: The increased intestinal calcium absorption is an indirect effect because PTH stimulates the activation of vitamin D, and calcitriol then increases intestinal calcium absorption.
d) Increasing osteoclast activity: This is a direct effect-PTH binds to osteoblasts, which signal osteoclasts to break down bone and release calcium.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
a) They cross the plasma membrane.
Amino acid-based hormones are water-soluble and cannot easily cross the lipid bilayer of the plasma membrane.
b) They are lipid soluble.
Unlike steroid hormones, amino acid-based hormones are not lipid-soluble; they are hydrophilic.
c) They are synthesized from cholesterol.
Steroid hormones are synthesized from cholesterol, not amino acid-based hormones.
d) They require a receptor in the plasma membrane.
Due to their inability to cross the plasma membrane, amino acid-based hormones bind to cell surface receptors to trigger intracellular responses via second messengers.
Correct Answer is C
Explanation
a) Activating vitamin D: This is a direct effect of PTH-PTH stimulates the activation of vitamin D (specifically, conversion to calcitriol) in the kidneys.
b) Increasing calcium reabsorption in the kidney: Also a direct effect-PTH acts on renal tubules to increase reabsorption of calcium.
c) Increasing calcium absorption in the intestines: The increased intestinal calcium absorption is an indirect effect because PTH stimulates the activation of vitamin D, and calcitriol then increases intestinal calcium absorption.
d) Increasing osteoclast activity: This is a direct effect-PTH binds to osteoblasts, which signal osteoclasts to break down bone and release calcium.
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