Which of the following is due to the inability to produce collagen or producing a defective collagen?
osteoporosis
osteogenesis imperfecta
osteomalacia
osteoarthritis
osteopetrosis
The Correct Answer is B
A. osteoporosis
This is a condition of reduced bone mass, often due to calcium/Vitamin D deficiency or hormonal imbalance-not defective collagen.
B. osteogenesis imperfecta
Known as “brittle bone disease”, osteogenesis imperfecta is a genetic disorder caused by defective or insufficient type I collagen, leading to fragile bones.
C. osteomalacia
Caused by Vitamin D deficiency, leading to soft bones due to defective mineralization, not collagen defects.
D. osteoarthritis
Degeneration of articular cartilage due to aging or wear-and-tear, not a collagen production issue.
E. osteopetrosis
A bone resorption disorder due to defective osteoclasts, resulting in abnormally dense but brittle bones-not due to collagen abnormalities.
F. fibrodysplasia ossificans progressiva
A rare genetic disorder in which soft tissue gradually turns into bone, unrelated to collagen production.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. occurs constantly during a person's lifetime
Bone is a dynamic tissue. Remodeling occurs throughout life to adapt to stress, repair microfractures, and regulate calcium levels.
B. is involved in Na⁺ regulation
Bone remodeling primarily involves calcium and phosphate regulation, not sodium.
C. only occurs after a bone has been broken and is healing
Remodeling happens continuously, not just after fractures. Healing is one scenario, but it's not exclusive.
D. does not occur when bones adjust to particular stresses
False. One of the main purposes of remodeling is to adapt to mechanical stress (e.g., weightlifting increases bone density).
Correct Answer is B
Explanation
A. spongy bone
Spongy bone (aka cancellous bone) is mature bone with a trabecular structure, not necessarily immature.
B. woven bone
Woven bone is immature bone characterized by random collagen fiber orientation. It is laid down rapidly in fetal development or fracture repair and is later replaced by lamellar bone.
C. lamellar bone
Lamellar bone is mature, organized bone, with parallel collagen fibers. It replaces woven bone during remodeling.
D. cancellous bone
Same as spongy bone-this is not immature bone.
E. compact bone
Compact bone is a mature form of bone found in the diaphysis of long bones, not the initial immature type.
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