Which of the following is not normally found in plasma?
Glycogen.
Fibrinogen.
Glucose.
Urea.
The Correct Answer is A
Choice A rationale
Glycogen is the storage form of glucose, primarily found within cells, particularly liver and muscle cells, as a readily accessible energy reserve. It is a polysaccharide, and its presence in plasma is not typical because glucose is the primary circulating carbohydrate, maintained at a narrow homeostatic range (normal fasting plasma glucose: 70-99 mg/dL or 3.9-5.5 mmol/L) for cellular energy.
Choice B rationale
Fibrinogen is a soluble plasma protein synthesized by the liver, crucial for hemostasis. Upon activation by thrombin, it polymerizes into insoluble fibrin strands, forming the structural meshwork of a blood clot, essential for stopping bleeding. Its normal concentration in plasma is approximately 200-400 mg/dL.
Choice C rationale
Glucose is a monosaccharide, the body's main source of energy, and is transported in the plasma to cells throughout the body for metabolic processes. Its concentration is tightly regulated by hormones like insulin and glucagon to ensure adequate cellular fuel while preventing hyperglycemia or hypoglycemia.
Choice D rationale
Urea is a metabolic waste product derived from the breakdown of proteins, specifically from the deamination of amino acids in the liver. It is transported in the plasma to the kidneys for excretion in urine, playing a vital role in nitrogenous waste elimination. Normal blood urea nitrogen (BUN) levels range from 7-20 mg/dL.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Vaccination works by introducing attenuated (weakened) or inactivated forms of pathogens, or specific pathogen components (antigens), into the body. This exposure triggers the immune system to mount a primary immune response, leading to the production of antibodies and memory cells without causing the actual disease, thus providing future protection.
Choice B rationale
Antibiotics are antimicrobial drugs that directly kill or inhibit the growth of bacteria. They are not involved in stimulating the body's immune system for long-term immunity; instead, they provide a direct therapeutic intervention against bacterial infections.
Choice C rationale
Vaccination aims to increase the body's resistance to disease, not its susceptibility. By priming the immune system with harmless forms of pathogens, vaccines enhance the body's ability to quickly and effectively combat future infections, thereby reducing susceptibility.
Choice D rationale
Vaccination does not suppress the immune system's natural response; rather, it activates and enhances it. The purpose of a vaccine is to stimulate a controlled immune response that leads to the development of immunological memory, preparing the immune system for real pathogen exposure.
Correct Answer is B
Explanation
Choice A rationale
Positive feedback mechanisms amplify the initial stimulus, leading to an increased response. While important in certain physiological processes like childbirth (oxytocin release) or blood clotting, it is less common for target organs to regulate pituitary function through this method, as it can lead to instability.
Choice B rationale
Negative feedback is the predominant mechanism by which target organs regulate pituitary function. High levels of target gland hormones inhibit the release of stimulating hormones from the pituitary and hypothalamus, thus maintaining hormonal homeostasis and preventing overproduction or underproduction.
Choice C rationale
Neural stimulation involves direct nerve impulses influencing hormone release, as seen in the adrenal medulla's response to sympathetic nervous system activation. While the hypothalamus has neural connections to the pituitary, direct neural stimulation from target organs is not the primary regulatory mechanism for pituitary control.
Choice D rationale
Direct hormonal release from target organs without involving feedback loops would result in unregulated hormone secretion, disrupting endocrine balance. Target organs typically release hormones that, in turn, exert feedback effects on the pituitary or hypothalamus, ensuring precise control and preventing dysregulation.
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