Which of the following pairs of blood tests is appropriate for a fasting specimen?
Glucose and triglycerides
BUN and alkaline phosphatase
Creatinine and total protein
Lactate dehydrogenase and albumin
The Correct Answer is A
Choice A reason:
Glucose and triglyceride levels are influenced by recent food intake, so it is essential to measure these levels after a period of fasting to obtain accurate results. Fasting ensures that the glucose measurement reflects the body's baseline glucose level without the influence of a recent meal, which is crucial for diagnosing and managing conditions like diabetes. Similarly, triglycerides, which are fats in the blood, can be elevated after eating, so a fasting sample gives a clear picture of the lipid profile for assessing cardiovascular risk.
Choice B reason:
While BUN (Blood Urea Nitrogen) levels can be affected by diet, fasting is not typically required for BUN or alkaline phosphatase tests. These tests are often part of a comprehensive metabolic panel that may or may not require fasting. However, fasting is not specifically necessary for accurate measurement of these two tests.
Choice C reason:
Creatinine and total protein levels are generally not affected by short-term dietary intake, so fasting is not required for these tests. Creatinine is a waste product from muscle metabolism and is used to evaluate kidney function, while total protein levels can indicate a variety of conditions including liver and kidney disorders, but they reflect the body's long-term nutritional status rather than immediate food intake.
Choice D reason:
Lactate dehydrogenase (LDH) and albumin tests do not require fasting. LDH is an enzyme found in almost all body tissues and is released into the bloodstream when tissues are damaged, so its levels are not dependent on food intake. Albumin is the most abundant protein in the blood and is produced by the liver; its levels are used to assess liver and kidney function, nutritional status, and other conditions, but fasting is not necessary for accurate measurement.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A Reason:
A glucose tolerance test is used to diagnose diabetes by measuring the body's response to glucose over a period of time. It is not used to identify bacteremia, which is the presence of bacteria in the bloodstream.
Choice B Reason:
A peripheral blood smear involves examining a sample of blood under a microscope to look for abnormalities in blood cells. While it can reveal signs of infection, it does not specifically identify bacteremia.
Choice C Reason:
A blood culture is the primary test used to detect bacteremia. It involves taking a sample of blood and incubating it to see if bacteria grow, which would indicate the presence of bacteria in the bloodstream.
Choice D Reason:
Lactic acid levels in the blood are measured to assess the severity of sepsis, a condition that can result from bacteremia. Elevated lactic acid can indicate that tissues are not getting enough oxygen, but the test itself does not identify bacteremia.
Correct Answer is D
Explanation
Choice A Reason:
Inverting the tube 5 to 7 times may not be sufficient to mix the blood thoroughly with the EDTA. This could lead to partial clotting and potentially inaccurate test results. The EDTA anticoagulant works by binding calcium ions, which are necessary for blood clotting. Without adequate mixing, the EDTA may not be evenly distributed, leaving some areas of the blood sample able to clot.
Choice B Reason:
Inverting the tube only 2 to 4 times is inadequate for proper mixing. This minimal agitation would likely result in clot formation because the anticoagulant would not be sufficiently mixed with the blood. Clots can interfere with the accuracy of hematological tests by trapping cells and altering the specimen's composition.
Choice C Reason:
Inverting the tube 1 to 3 times is clearly insufficient and would almost certainly lead to clotting. The purpose of inverting the tube is to ensure that the EDTA coats all the blood cells, preventing coagulation. Such a low number of inversions would not allow for the anticoagulant to perform its function effectively.
Choice D Reason:
Inverting the tube 8 to 10 times is the recommended practice. This number of inversions ensures that the blood is fully mixed with the EDTA, preventing clot formation and preserving the integrity of the sample for accurate laboratory analysis. It is important to perform these inversions gently to avoid hemolysis, which can also affect test results. Hemolysis occurs when red blood cells are damaged and their contents leak out, which can happen if the blood is shaken too vigorously.
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