Which of the following statements best describes the effect of Donepezil on Alzheimer’s disease?

A. "I should report a persistent cough to my provider.": A dry, persistent cough is a common side effect of ACE inhibitors like Lisinopril. Reporting this symptom is important, as the provider may consider switching to another class of antihypertensives if it becomes bothersome.
B. "I should take this medication as needed.": Lisinopril must be taken consistently every day to manage blood pressure effectively. Taking it only when symptoms are present is inappropriate and can lead to poor control and serious complications.
C. "I should expect to have facial swelling when taking this medication.": Facial swelling (angioedema) is a serious and potentially life-threatening adverse effect, not something to expect or tolerate. If it occurs, the medication should be stopped and medical help sought immediately.
D. "I should increase my intake of potassium-rich foods.": Lisinopril can increase serum potassium levels, leading to hyperkalemia. Clients should be advised to avoid excessive potassium intake and may need periodic lab monitoring.

A. "Barbiturates carry a higher risk of dependence and overdose compared to other sedative-hypnotics.": Barbiturates have a narrow therapeutic index, and overdose can lead to fatal respiratory depression. Their high abuse potential and severe withdrawal symptoms make them less favorable than safer alternatives like benzodiazepines.
B. "Barbiturates are more expensive than newer medications like benzodiazepines, which limits their use.": Cost is not the primary reason for their reduced use. In fact, many barbiturates are inexpensive. Their safety profile and high risk of fatal overdose are the major concerns.
C. "Barbiturates have been replaced because they are less effective than over-the-counter sleep aids.": Barbiturates are actually very potent sedative-hypnotics. However, their risks outweigh their benefits. OTC sleep aids are less effective but considered safer for short-term use.
D. "Barbiturates are safer for long-term use compared to other sedatives, but they have limited availability.": Barbiturates are not safer for long-term use. They are associated with tolerance, dependence, cognitive impairment, and severe withdrawal, which is why their use has been largely replaced.