A patient is prescribed Cholestyramine to lower their cholesterol levels. Which of the following instructions should the nurse provide to the patient regarding the timing of taking this medication?

Take Cholestyramine with other medications to improve absorption

Take the powder for oral suspension in dry form

Take after meals

Take other medications at least 1 hour before or 4 hours after taking Cholestyramine

Answer and Explanation

The Correct Answer is D

A. Take Cholestyramine with other medications to improve absorption: Cholestyramine binds bile acids in the intestine but can also bind and interfere with the absorption of other oral medications. Taking it with other drugs reduces their effectiveness and is not recommended.
B. Take the powder for oral suspension in dry form: Cholestyramine powder should never be taken dry as it can irritate the mouth, throat, and gastrointestinal tract. It should always be mixed with water or a non-carbonated beverage before ingestion to prevent choking or esophageal irritation.
C. Take after meals: While taking it after meals can enhance its bile acid-binding effect, this alone does not prevent drug interactions. Timing with other medications is the more critical issue to address when instructing patients.
D. Take other medications at least 1 hour before or 4 hours after taking Cholestyramine: This instruction is essential to avoid interference with the absorption of other oral medications. Cholestyramine can bind many drugs, so proper spacing is required to ensure therapeutic efficacy of concurrent medications.

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Correct Answer is A

Explanation

A. "All antipsychotic drugs carry an equal risk of causing movement-related side effects.": First-generation antipsychotics like Haloperidol are more likely to cause extrapyramidal symptoms due to their potent dopamine D2 receptor blockade. Second-generation antipsychotics carry a lower risk, making this statement inconsistent with clinical evidence.
B. "These side effects happen because this drug blocks dopamine in certain parts of my brain.": Extrapyramidal symptoms are primarily due to dopamine blockade in the nigrostriatal pathway, which regulates motor control. Interference in this region leads to tremors, rigidity, and other movement disorders.
C. "Taking other drugs with my Haloperidol can increase the risk of extrapyramidal symptoms.": Concurrent use of medications that also affect dopamine pathways or have sedative effects can increase the likelihood of developing EPS. Drug interactions are a significant factor in overall risk.
D. "Tardive dyskinesia occurs with prolonged use of an antipsychotic drug.": Long-term use of dopamine-blocking agents, especially at high doses, can lead to tardive dyskinesia. This condition involves involuntary movements and may be irreversible, particularly in older adults.

A. Cushing's syndrome B. Adrenal insufficiency C. Diabetes mellitus D. Dystonia

Correct Answer is A

Explanation

A. Cushing's syndrome: Prolonged use of corticosteroids can lead to iatrogenic Cushing's syndrome. Common features include weight gain (especially central), mood changes such as anxiety or irritability, insomnia, and physical changes like hirsutism (increased facial hair), moon face, and truncal obesity due to chronic hypercortisolism.
B. Adrenal insufficiency: This condition typically results from abrupt withdrawal of corticosteroids, leading to fatigue, hypotension, and electrolyte imbalances. It does not cause the excess cortisol-related symptoms described in this patient’s presentation.
C. Diabetes mellitus: While corticosteroids can raise blood glucose levels and increase the risk for diabetes, the described symptoms—particularly the weight distribution and hirsutism—are more indicative of Cushing’s syndrome than diabetes.
D. Dystonia: Dystonia involves involuntary muscle contractions causing repetitive movements or abnormal postures. It is not associated with the metabolic and hormonal effects caused by long-term corticosteroid use.

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A patient is prescribed Cholestyramine to lower their cholesterol levels. Which of the following instructions should the nurse provide to the patient regarding the timing of taking this medication?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is educating a patient who has been prescribed Haloperidol about the risk of extrapyramidal symptoms. Which of the following statements by the patient indicates a need for further teaching?

Correct Answer is A

Explanation

A 38-year-old female has been on corticosteroids for several months to manage severe asthma exacerbations. The patient reports weight gain, feeling anxious, experiencing insomnia, and noticing increased facial hair growth. Which of the following is the most likely explanation for these symptoms?

Correct Answer is A

Explanation

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