Analyze the following clinical manifestations and determine whether they are characteristic of Anticholinergic or Cholinergic Toxicity.
Hypertension
Urinary Retention
Diaphoresis
Bronchoconstriction
Salivation
Hyperthermia
The Correct Answer is {"A":{"answers":"A"},"B":{"answers":"A"},"C":{"answers":"B"},"D":{"answers":"B"},"E":{"answers":"B"},"F":{"answers":"A"}}
- Hypertension: Seen in anticholinergic toxicity due to decreased parasympathetic tone and possible unopposed sympathetic stimulation. The body's inability to relax vascular tone may contribute to elevated blood pressure.
- Urinary Retention: A classic feature of anticholinergic toxicity. Inhibition of muscarinic receptors leads to impaired detrusor muscle contraction, making urination difficult or impossible.
- Hyperthermia: Results from inhibited sweating (anhidrosis), which is a hallmark of anticholinergic toxicity. Without the ability to cool through evaporation, body temperature rises dangerously.
- Diaphoresis: Excessive sweating is mediated by muscarinic receptor activation in cholinergic toxicity. It's often part of the SLUDGE symptoms seen in organophosphate poisoning or cholinesterase inhibitor overdose.
- Bronchoconstriction: Caused by overstimulation of muscarinic receptors in the airways, leading to narrowed bronchi and increased respiratory secretions — a dangerous feature of cholinergic excess.
- Salivation: Prominent in cholinergic toxicity due to unopposed parasympathetic activation. It may occur along with lacrimation, bradycardia, and other signs of excessive cholinergic stimulation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. "Limit your fluid intake to meal times.": Fluid restriction is not a standard recommendation for patients taking Verapamil unless they have another condition like heart failure. Adequate hydration is important, especially to counter constipation, a known side effect of the drug.
B. "You can expect swelling of the ankles while taking this medication.": While peripheral edema is a known side effect of Verapamil, it is not something patients should expect or accept without reporting. Significant swelling may require dose adjustment or switching medications.
C. "This medication will not affect your heart rate": Verapamil is a calcium channel blocker that slows AV node conduction and reduces heart rate. It is used for conditions like hypertension, angina, and arrhythmias, and can cause bradycardia, especially in high doses.
D. "Increase your daily intake of dietary fiber.": Verapamil frequently causes constipation by decreasing gastrointestinal motility. Increasing dietary fiber, fluid intake, and physical activity are recommended to minimize this side effect and promote regular bowel movements.
Correct Answer is B
Explanation
A. "The oral medication you will take after this IV will dissolve the clot.": Oral anticoagulants like warfarin also do not dissolve existing clots. They work similarly to heparin by preventing the formation of new clots and allowing the body’s natural fibrinolytic mechanisms to break down existing ones over time.
B. "Heparin does not dissolve clots. It stops new clots from forming.": This is the most accurate explanation. Heparin is an anticoagulant that enhances antithrombin activity, inhibiting clotting factors and preventing clot propagation, but it does not actively lyse or dissolve clots.
C. "It usually takes heparin at least 2 to 3 days to reach a therapeutic blood level.": Heparin given intravenously has a rapid onset of action, often within minutes. Therapeutic levels are typically reached quickly with continuous infusion, so this statement is inaccurate.
D. "A pharmacist is the person to answer that question.": While pharmacists are valuable for drug-related questions, nurses are expected to provide basic patient education regarding medications, including mechanism of action, especially during bedside care.
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