Which organ is primarily responsible for excretion of a medication?

Kidneys

Pancreas

Gallbladder

Liver

Answer and Explanation

The Correct Answer is A

Choice A reason: This is correct. The kidneys are the main organs for excreting water-soluble substances, including most drugs and their metabolites. The kidneys filter the blood and remove waste products and excess fluid as urine. Drugs can be excreted by glomerular filtration, tubular secretion, or tubular reabsorption.

Choice B reason: This is incorrect. The pancreas is not involved in excretion of drugs. The pancreas is an organ that produces digestive enzymes and hormones, such as insulin and glucagon.

Choice C reason: This is incorrect. The gallbladder is not involved in excretion of drugs. The gallbladder is an organ that stores and concentrates bile, a fluid that helps digest fats.

Choice D reason: This is incorrect. The liver is not primarily responsible for excretion of drugs, although it plays an important role in drug metabolism. The liver is an organ that performs many functions, such as detoxifying substances, synthesizing proteins, and producing bile. The liver can transform drugs into more polar and water-soluble compounds, which can then be excreted by the kidneys or the biliary system.

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Correct Answer is A

Explanation

Choice A reason: This is correct. Constipation is a common side effect of aluminum hydroxide, as it reduces the motility of the gastrointestinal tract. The nurse should advise the client to report this symptom and to increase their fluid and fiber intake to prevent it.

Choice B reason: This is incorrect. Flatulence is not a common side effect of aluminum hydroxide. It may be caused by other factors, such as diet, swallowing air, or bacterial overgrowth in the intestines.

Choice C reason: This is incorrect. Headache is not a common side effect of aluminum hydroxide. It may be caused by other factors, such as stress, dehydration, or caffeine withdrawal.

Choice D reason: This is incorrect. Palpitations are not a common side effect of aluminum hydroxide. They may be caused by other factors, such as anxiety, heart problems, or medication interactions.

A. Past medical history of benign prostatic hyperplasia (BPH) B. Blood pressure of 132/82 C. Allergy to corn D. Past medical history of gout

Correct Answer is C

Explanation

Choice A reason: Past medical history of benign prostatic hyperplasia (BPH) is not a contraindication or a concern for administering Reglan, which is a medication that stimulates the motility of the upper gastrointestinal tract and treats nausea, heartburn, and gastroparesis¹. Reglan does not affect the prostate or urinary function.

Choice B reason: Blood pressure of 132/82 is slightly above the normal range of 120/80, but it is not a cause for concern or a reason to withhold Reglan. Reglan can lower the blood pressure by reducing the fluid volume and preventing sodium retention¹. The nurse should monitor the blood pressure regularly, but does not need to notify the health care provider about this finding.

Choice C reason: Allergy to corn is a concern for administering Reglan, as some formulations of Reglan may contain corn starch as an inactive ingredient. Corn starch can trigger an allergic reaction in people who are sensitive to corn, causing symptoms such as rash, itching, swelling, or anaphylaxis. The nurse should check the label of the Reglan product and avoid using it if it contains corn starch. The nurse should also notify the health care provider and the pharmacy about the patient's allergy and request an alternative medication or formulation.

Choice D reason: Past medical history of gout is not a contraindication or a concern for administering Reglan, which is a medication that stimulates the motility of the upper gastrointestinal tract and treats nausea, heartburn, and gastroparesis¹. Reglan does not affect the uric acid levels or the joints.

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Which organ is primarily responsible for excretion of a medication?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is teaching a client who has a new prescription for aluminum hydroxide to treat heartburn. The nurse should instruct the client to monitor for and report which of the following adverse reactions?

Correct Answer is A

Explanation

The nurse is preparing to administer Reglan to a patient. She is most concerned by the following information in the patient's medical record?

Correct Answer is C

Explanation

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