Which statement is correct about patient tolerance to medications?

The patient will continually require higher doses of the drug for the same effect to be achieved.

Tolerance occurs when the liver or kidneys are no longer able to metabolize the drug.

The patient will require a stable dose of the medication until the drug is discontinued.

Tolerance only develops when the patients do not take the medication as it is prescribed.

Answer and Explanation

The Correct Answer is A

Choice A reason: Tolerance reflects receptor desensitization or enzyme induction; higher doses compensate for reduced drug efficacy, a common pharmacological adaptation.

Choice B reason: Organ failure affects metabolism, not tolerance; tolerance is a cellular response, not solely a failure of liver or kidney drug clearance mechanisms.

Choice C reason: Stable dosing contradicts tolerance; if tolerance develops, efficacy drops, necessitating dose increases, not maintenance, to achieve therapeutic levels.

Choice D reason: Non-adherence may alter response, but tolerance occurs with consistent use; it’s a physiological adaptation, not a result of misuse or skipping doses.

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Correct Answer is D

Explanation

Choice A reason: Two-hour window (8:00-10:00) is too broad; most protocols allow 30 minutes before/after, as wider ranges risk altering drug pharmacokinetics significantly.

Choice B reason: One-hour window (8:30-9:30) is common but exceeds some strict policies; it’s less precise, potentially affecting drugs with tight timing needs.

Choice C reason: 8:30-9:00 is only before; it excludes post-9:00 flexibility, limiting administration to early dosing, which may not align with full protocol windows.

Choice D reason: 8:45-9:15 (30 minutes either side) fits standard policy; it ensures therapeutic levels for most drugs, balancing efficacy with practical scheduling.

A. Crush the pills and mix them with applesauce. B. Have the primary health provider prescribe the liquid form of this drug. C. Use the paper cup to introduce the pills into the patient's mouth. D. Put the pills in the patient’s hand and have the patient self-administer the pills.

Correct Answer is B

Explanation

Choice A reason: Crushing pills can alter drug efficacy and safety, especially for medications with controlled-release properties, making this inappropriate without specific provider instructions.

Choice B reason: Requesting a liquid form accommodates the patient’s physical limitations, maintaining therapeutic integrity and ensuring safe and effective medication administration.

Choice C reason: Introducing pills directly into the patient’s mouth risks aspiration and violates safe administration practices, emphasizing the need for alternative methods.

Choice D reason: If the patient struggles to hold the cup, self-administration becomes impractical. Assistance through appropriate alternative forms ensures compliance and safety.

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Which statement is correct about patient tolerance to medications?

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Naxlex Comprehensive Predictor Exams

A client is to receive a medication at 9:00 A.M. To prevent a medication error by administering at the incorrect time, the nurse can administer the medication anytime between:

Correct Answer is D

Explanation

When the nurse brings pills to the patient, the patient is unable to hold the paper cup with the medications. What should the nurse do?

Correct Answer is B

Explanation

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