Which statement is correct about patient tolerance to medications?

The patient will continually require higher doses of the drug for the same effect to be achieved.

Tolerance occurs when the liver or kidneys are no longer able to metabolize the drug.

The patient will require a stable dose of the medication until the drug is discontinued.

Tolerance only develops when the patients do not take the medication as it is prescribed.

Answer and Explanation

The Correct Answer is A

Choice A reason: Tolerance reflects receptor desensitization or enzyme induction; higher doses compensate for reduced drug efficacy, a common pharmacological adaptation.

Choice B reason: Organ failure affects metabolism, not tolerance; tolerance is a cellular response, not solely a failure of liver or kidney drug clearance mechanisms.

Choice C reason: Stable dosing contradicts tolerance; if tolerance develops, efficacy drops, necessitating dose increases, not maintenance, to achieve therapeutic levels.

Choice D reason: Non-adherence may alter response, but tolerance occurs with consistent use; it’s a physiological adaptation, not a result of misuse or skipping doses.

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Correct Answer is A

Explanation

Choice A reason: Consulting ensures safety; not all drugs can be altered, and the provider adjusts the order, preventing errors in bioavailability or efficacy.

Choice B reason: Liquid may work, but without approval, it’s unauthorized; some drugs lack liquid forms, and this bypasses necessary prescriber oversight.

Choice C reason: Parenteral needs an order change; administering without it violates scope, and it’s invasive, escalating care unnecessarily as a first step.

Choice D reason: Crushing alters pharmacokinetics; many tablets (e.g., extended-release) can’t be crushed, and doing so without checking risks toxicity or inefficacy.

A. 6:00 a.m., 12:00 noon, 6:00 p.m., 12:00 midnight B. 6:00 a.m., 10:00 a.m., 2:00 p.m., 6:00 p.m., 10:00 p.m., 2:00 a.m. C. 9:00 a.m., 1:00 p.m., 5:00 p.m. D. Before the patient’s meals and at bedtime

Correct Answer is C

Explanation

Choice A reason: Four times (6:00 a.m., noon, 6:00 p.m., midnight) is QID, not TID; TID means three times daily, and this schedule overdoses the patient unnecessarily.

Choice B reason: Six times daily is every 4 hours, not TID; this exceeds the three-dose requirement, risking toxicity or side effects from excessive administration frequency.

Choice C reason: 9:00 a.m., 1:00 p.m., 5:00 p.m. is TID; spaced 8 hours apart, it aligns with standard three-times-daily dosing, ensuring consistent therapeutic levels safely.

Choice D reason: Meal and bedtime timing is vague; without fixed hours, it risks uneven dosing intervals, potentially disrupting pharmacokinetics and efficacy of the medication.

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Which statement is correct about patient tolerance to medications?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is caring for a client who has difficulty swallowing a large tablet of a prescribed drug. What action should the nurse take first?

Correct Answer is A

Explanation

The patient's medication is ordered to be administered TID. Which times will be entered into the patient's medication schedule?

Correct Answer is C

Explanation

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