Which statement is correct about patient tolerance to medications?

The patient will continually require higher doses of the drug for the same effect to be achieved.

Tolerance occurs when the liver or kidneys are no longer able to metabolize the drug.

The patient will require a stable dose of the medication until the drug is discontinued.

Tolerance only develops when the patients do not take the medication as it is prescribed.

Answer and Explanation

The Correct Answer is A

Choice A reason: Tolerance reflects receptor desensitization or enzyme induction; higher doses compensate for reduced drug efficacy, a common pharmacological adaptation.

Choice B reason: Organ failure affects metabolism, not tolerance; tolerance is a cellular response, not solely a failure of liver or kidney drug clearance mechanisms.

Choice C reason: Stable dosing contradicts tolerance; if tolerance develops, efficacy drops, necessitating dose increases, not maintenance, to achieve therapeutic levels.

Choice D reason: Non-adherence may alter response, but tolerance occurs with consistent use; it’s a physiological adaptation, not a result of misuse or skipping doses.

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Correct Answer is B

Explanation

Choice A reason: Juice may alter absorption; liquid can dilute or degrade some drugs, and taste may deter intake, reducing effectiveness compared to soft food.

Choice B reason: Applesauce masks taste and aids swallowing; it ensures crushed medication is consumed fully, maintaining dose integrity without altering pharmacokinetics significantly.

Choice C reason: Water may not mask bitterness; some drugs dissolve poorly or lose potency, and patients may not finish it, risking incomplete dosing.

Choice D reason: Meat or vegetables may bind drugs; uneven distribution or strong flavors could reduce intake, compromising the full therapeutic dose delivery.

A. In the medication room B. Outside the door to the patient’s room C. At the medication cart D. At the patient’s bedside

Correct Answer is D

Explanation

Choice A reason: Removing in the medication room risks mix-ups; tablets could be dropped or misidentified before reaching the patient, compromising the three-check safety protocol.

Choice B reason: Outside the door is premature; without the patient present, verification against the MAR is incomplete, increasing error risk before final identity confirmation.

Choice C reason: At the cart is too early; medication stays packaged until bedside to ensure the right patient, right drug match, reducing handling errors or contamination.

Choice D reason: Bedside removal allows final MAR check with patient ID; it ensures accuracy, prevents mix-ups, and aligns with safety standards for administering oral medications.

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Which statement is correct about patient tolerance to medications?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is going to administer a medication that must be crushed for the patient to take it. This medication is best given to the patient by:

Correct Answer is B

Explanation

A nurse is preparing to administer a tablet to the patient. When should the nurse remove the medication from its unit dose package?

Correct Answer is D

Explanation

Which statement is correct about patient tolerance to medications?

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