Which statement is correct about patient tolerance to medications?
The patient will continually require higher doses of the drug for the same effect to be achieved.
Tolerance occurs when the liver or kidneys are no longer able to metabolize the drug.
The patient will require a stable dose of the medication until the drug is discontinued.
Tolerance only develops when the patients do not take the medication as it is prescribed.
The Correct Answer is A
Choice A reason: Tolerance reflects receptor desensitization or enzyme induction; higher doses compensate for reduced drug efficacy, a common pharmacological adaptation.
Choice B reason: Organ failure affects metabolism, not tolerance; tolerance is a cellular response, not solely a failure of liver or kidney drug clearance mechanisms.
Choice C reason: Stable dosing contradicts tolerance; if tolerance develops, efficacy drops, necessitating dose increases, not maintenance, to achieve therapeutic levels.
Choice D reason: Non-adherence may alter response, but tolerance occurs with consistent use; it’s a physiological adaptation, not a result of misuse or skipping doses.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Therapeutic effects define expected outcomes; knowing these (e.g., pain relief) lets the nurse assess if the drug meets its clinical goal effectively.
Choice B reason: Chemical composition informs structure, not outcome; it’s irrelevant to evaluating if the drug achieves its intended physiological effect directly.
Choice C reason: Mechanism explains how drugs work; it’s useful but secondary to knowing the actual therapeutic result needed for outcome assessment.
Choice D reason: Side effects monitor safety, not efficacy; they don’t directly measure if the drug achieves its primary therapeutic purpose as intended.
Correct Answer is B
Explanation
Choice A reason: Lisinopril is the generic name; trade names are branded, and this doesn’t fit the question’s focus on the manufacturer’s marketed title.
Choice B reason: Zestril is the trade name for lisinopril; it’s trademarked by the manufacturer, aligning with the question’s request for the branded medication name.
Choice C reason: Acetaminophen is a generic, not a trade name here; it’s unrelated to Zestril’s class (ACE inhibitor), making it an incorrect option.
Choice D reason: Morphine is a generic opioid; it doesn’t match Zestril’s antihypertensive role or trade name status, ruling it out entirely.
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