Which statement is correct about patient tolerance to medications?
The patient will continually require higher doses of the drug for the same effect to be achieved.
Tolerance occurs when the liver or kidneys are no longer able to metabolize the drug.
The patient will require a stable dose of the medication until the drug is discontinued.
Tolerance only develops when the patients do not take the medication as it is prescribed.
The Correct Answer is A
Choice A reason: Tolerance reflects receptor desensitization or enzyme induction; higher doses compensate for reduced drug efficacy, a common pharmacological adaptation.
Choice B reason: Organ failure affects metabolism, not tolerance; tolerance is a cellular response, not solely a failure of liver or kidney drug clearance mechanisms.
Choice C reason: Stable dosing contradicts tolerance; if tolerance develops, efficacy drops, necessitating dose increases, not maintenance, to achieve therapeutic levels.
Choice D reason: Non-adherence may alter response, but tolerance occurs with consistent use; it’s a physiological adaptation, not a result of misuse or skipping doses.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: Blood pressure matters but isn’t primary; opioids rarely cause acute hypotension initially, and respiratory depression is a more immediate life-threatening risk.
Choice B reason: Temperature is unrelated; opioids don’t primarily affect fever, and this assessment doesn’t address the critical safety concern of opioid administration.
Choice C reason: Pulse is secondary; opioids may slow heart rate mildly, but respiratory suppression is the urgent risk, requiring priority monitoring before dosing.
Choice D reason: Respiratory rate is critical; opioids depress the brainstem, risking apnea, and assessing breathing ensures safety before administering this high-risk medication.
Correct Answer is D
Explanation
Choice A reason: PRN is as needed; EKGs here are routine, not symptom-driven, making this inapplicable to a standard admission protocol for all patients.
Choice B reason: One-time is a single event; this order applies to all admissions ongoing, not a one-off, distinguishing it from limited-duration directives.
Choice C reason: STAT is immediate; routine EKGs aren’t urgent, occurring as part of standard care, not requiring the priority of acute intervention orders.
Choice D reason: Standing orders apply automatically to all qualifying patients; this EKG protocol fits, ensuring consistent cardiac assessment unless overridden.
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