Which statement made by the nurse explains the rationale for the use of donepezil for clients diagnosed with Alzheimer's dementia?
Donepezil increases the availability of acetylcholine at cholinergic synapses.
Donepezil decreases acetylcholine in the periphery to increase movement.
Donepezil delays transmission of acetylcholine at the neuronal junction.
Donepezil works to bind the dopamine at neuron receptor sites to increase ability.
The Correct Answer is A
Donepezil is a medication used to treat Alzheimer's dementia. Its main mechanism of action is the inhibition of the acetylcholinesterase enzyme in the brain ¹. This increases the availability of acetylcholine at cholinergic synapses ⁵, which can improve cognition and function in clients with Alzheimer's dementia ¹.
Option B is incorrect because donepezil does not decrease acetylcholine in the periphery to increase movement.
Option C is incorrect because donepezil does not delay the transmission of acetylcholine at the neuronal junction.
Option D is incorrect because donepezil does not bind dopamine at neuron receptor sites to increase ability.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Cyclobenzaprine is structurally similar to tricyclic antidepressants (TCAs) and has similar anticholinergic side effects ³. Common anticholinergic side effects of cyclobenzaprine include dry mouth ¹⁵, constipation ¹⁵, and photophobia ³.
Option A is not correct because bradycardia is not a common side effect of cyclobenzaprine.
Option C is not correct because muscle rigidity, restless movements, and tremors are not common side effects of cyclobenzaprine.
Option D is not correct because flushing, tachycardia, and hives are not common side effects of cyclobenzaprine.
Correct Answer is C
Explanation
The nurse would want to have flumazenil readily available in case benzodiazepine reversal is needed. Flumazenil is a medication used to reverse the effects of benzodiazepines such as lorazepam ¹. It can be used to help a person wake up after a medical procedure in which a benzodiazepine was used as a sedative or to treat a benzodiazepine overdose ¹.
Option A is incorrect because physostigmine is not used to reverse the effects of benzodiazepines.
Option B is incorrect because naloxone is used to reverse the effects of opioids, not benzodiazepines.
Option D is incorrect because syrup of ipecac is not used to reverse the effects of benzodiazepines.
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