Which statement made by the nurse explains the rationale for the use of donepezil for clients diagnosed with Alzheimer's dementia?
Donepezil increases the availability of acetylcholine at cholinergic synapses.
Donepezil decreases acetylcholine in the periphery to increase movement.
Donepezil delays transmission of acetylcholine at the neuronal junction.
Donepezil works to bind the dopamine at neuron receptor sites to increase ability.
The Correct Answer is A
Donepezil is a medication used to treat Alzheimer's dementia. Its main mechanism of action is the inhibition of the acetylcholinesterase enzyme in the brain ¹. This increases the availability of acetylcholine at cholinergic synapses ⁵, which can improve cognition and function in clients with Alzheimer's dementia ¹.
Option B is incorrect because donepezil does not decrease acetylcholine in the periphery to increase movement.
Option C is incorrect because donepezil does not delay the transmission of acetylcholine at the neuronal junction.
Option D is incorrect because donepezil does not bind dopamine at neuron receptor sites to increase ability.
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Related Questions
Correct Answer is D
Explanation
Donepezil is a medication that can cause side effects such as dizziness and fainting ¹. Therefore, it is important for the client to rise slowly from a lying or sitting position to prevent falls.
Option A is incorrect because donepezil can be taken with or without food.
Option B is incorrect because donepezil does have side effects ¹.
Option C is incorrect because the health care provider added donepezil to the client's daily routine, not to replace carbidopa/levodopa.
Correct Answer is C
Explanation
Dantrolene is a medication that can be used to manage symptoms of malignant hyperthermia ¹. Malignant hyperthermia is a life-threatening reaction to certain medications used during general anesthesia ².
Dantrolene works by inhibiting the release of calcium in the muscles, which helps control the condition and restore normal vital signs ³.
Option A is not correct because baclofen is not used to manage symptoms of malignant hyperthermia.
Option B is not correct because diazepam is not used to manage symptoms of malignant hyperthermia.
Option D is not correct because tizanidine is not used to manage symptoms of malignant hyperthermia.
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