Which statement made by the nurse explains the rationale for the use of donepezil for clients diagnosed with Alzheimer's dementia?
Donepezil increases the availability of acetylcholine at cholinergic synapses.
Donepezil decreases acetylcholine in the periphery to increase movement.
Donepezil delays transmission of acetylcholine at the neuronal junction.
Donepezil works to bind the dopamine at neuron receptor sites to increase ability.
The Correct Answer is A
Donepezil is a medication used to treat Alzheimer's dementia. Its main mechanism of action is the inhibition of the acetylcholinesterase enzyme in the brain ¹. This increases the availability of acetylcholine at cholinergic synapses ⁵, which can improve cognition and function in clients with Alzheimer's dementia ¹.
Option B is incorrect because donepezil does not decrease acetylcholine in the periphery to increase movement.
Option C is incorrect because donepezil does not delay the transmission of acetylcholine at the neuronal junction.
Option D is incorrect because donepezil does not bind dopamine at neuron receptor sites to increase ability.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","C","D","E"]
Explanation
The common adverse effects of fluoxetine that the nurse should include in their health teaching are nervousness, dry mouth, decreased libido, and insomnia ². These are all known side effects of fluoxetine and can occur in some people who take the medication.
Option A is incorrect because low-grade fever is not a common side effect of fluoxetine.
Option f is incorrect because bradycardia (slow heart rate) is not a common side effect of fluoxetine.
Correct Answer is ["A","D"]
Explanation
A. Tolerance can develop over time and lead to the need for higher doses – This is correct because long-term use of clonazepam, like other benzodiazepines, can result in tolerance, potentially necessitating higher doses to achieve the same therapeutic effect.
B. Skip a dose if you need to drive – This is incorrect. Clients should be advised to take their medication as prescribed and consult their healthcare provider about driving, as clonazepam can impair coordination and reaction times.
C. Skip a dose if you plan to go out drinking with friends – This is incorrect. While it’s important to avoid alcohol when taking clonazepam due to the increased risk of sedation and respiratory depression, clients should not skip doses without consulting their healthcare provider.
D. Do not try to taper yourself off this medication without physician guidance – This is correct. Stopping clonazepam suddenly can lead to withdrawal symptoms and seizure recurrence, so any changes in medication should always be done under the guidance of a healthcare provider.
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