Which symptom reported by a client alerts the practical nurse (PN) to withhold a scheduled dose of hydrochlorothiazide and notify the healthcare provider?
Palpitations
Nervousness
Nausea
Anorexia
The Correct Answer is A
Choice A reason: Palpitations may indicate electrolyte imbalances, like hypokalemia, a serious side effect of hydrochlorothiazide, a thiazide diuretic. It increases potassium excretion, disrupting cardiac electrical activity, potentially causing arrhythmias. Withholding the dose and notifying the provider is critical to prevent life-threatening cardiac complications, requiring urgent electrolyte assessment.
Choice B reason: Nervousness is a vague symptom not typically linked to hydrochlorothiazide’s side effects. It may reflect anxiety or other unrelated issues, not necessitating immediate drug cessation. Electrolyte imbalances or hypotension are more concerning, making this choice less urgent for withholding the medication.
Choice C reason: Nausea is a common, non-specific side effect of many medications, including hydrochlorothiazide, but is not severe enough to warrant withholding the dose. It may resolve or be managed symptomatically. More critical side effects, like electrolyte imbalances, take precedence, making this choice incorrect.
Choice D reason: Anorexia is not a primary concern with hydrochlorothiazide. While it may occur with diuretic-induced dehydration, it is less urgent than cardiac symptoms like palpitations. This symptom does not directly indicate a life-threatening side effect, so withholding the drug is not immediately necessary.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Antilipidemic medications, like statins, lower serum cholesterol by inhibiting HMG-CoA reductase, reducing low-density lipoprotein (LDL) production. Monitoring cholesterol levels, particularly LDL, directly assesses the drug’s effectiveness in reducing cardiovascular risk, as elevated cholesterol is the primary target of therapy.
Choice B reason: Hemoglobin A1C reflects blood glucose control, relevant for diabetes management, not lipid-lowering therapy. Antilipidemics target cholesterol, not glucose metabolism. This value is unrelated to the drug’s mechanism, making it irrelevant for assessing antilipidemic efficacy.
Choice C reason: INR monitors anticoagulation, relevant for drugs like warfarin, not antilipidemics. Cholesterol-lowering drugs do not affect clotting pathways. Monitoring INR is unnecessary, as it does not reflect the therapeutic goal of reducing lipid levels, making this choice incorrect.
Choice D reason: Platelet count assesses bleeding risk or bone marrow function, not lipid levels. Antilipidemics do not significantly affect platelets. Monitoring cholesterol is the direct measure of efficacy, as platelets are unrelated to the drug’s cholesterol-lowering mechanism, making this choice irrelevant.
Correct Answer is B
Explanation
Choice A reason: Observing ulcer healing is important in diabetic neuropathy but not a direct measure of pregabalin’s effectiveness. Pregabalin reduces neuropathic pain, not primarily promoting tissue repair. Ulcer healing depends on glycemic control and wound care, making this choice secondary.
Choice B reason: Measuring pain and sensation assesses pregabalin’s effectiveness, as it modulates calcium channels in neurons, reducing neuropathic pain and abnormal sensations in diabetic neuropathy. Decreased pain or paresthesia in the feet indicates therapeutic success, making this the most relevant assessment for the drug’s action.
Choice C reason: Palpating skin temperature evaluates circulation or infection, not pregabalin’s effect. While neuropathy may affect perfusion, pregabalin targets pain signaling, not temperature regulation. This assessment is unrelated to the drug’s primary role in pain management, making it irrelevant.
Choice D reason: Checking swelling monitors edema, which may occur in diabetes but is not pregabalin’s target. The drug reduces neuropathic pain, not fluid accumulation. Swelling assessment is secondary to pain and sensation, which directly reflect the medication’s efficacy in neuropathy management.
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