Which term describes the inflammatory mediator released during the early phase of type 1 hypersensitivity response causing immediate bronchoconstriction and vasodilation?
Prostaglandins
Histamine
Leukotrienes
Bradykinin
The Correct Answer is B
Choice A reason: Prostaglandins are inflammatory mediators that are derived from arachidonic acid. They are involved in both the early and late phases of type 1 hypersensitivity response, but they do not cause immediate bronchoconstriction and vasodilation. They mainly cause pain, fever, and inflammation.
Choice B reason: Histamine is an inflammatory mediator that is stored in mast cells and basophils. It is released during the early phase of type 1 hypersensitivity response, which occurs within minutes of exposure to an allergen. It causes immediate bronchoconstriction and vasodilation, as well as increased vascular permeability, mucus secretion, and itching.
Choice C reason: Leukotrienes are inflammatory mediators that are derived from arachidonic acid. They are involved in the late phase of type 1 hypersensitivity response, which occurs several hours after exposure to an allergen. They cause sustained bronchoconstriction and inflammation, as well as increased mucus production and airway edema.
Choice D reason: Bradykinin is an inflammatory mediator that is formed from plasma proteins. It is not directly involved in type 1 hypersensitivity response, but it may be activated by the complement system, which is part of the innate immune system. It causes vasodilation, increased vascular permeability, and pain.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: Hepatomegaly is not the expected finding because it is a condition where the liver is enlarged, which can be caused by various factors, such as infections, tumors, or cirrhosis. Hepatomegaly is not a common manifestation of systemic lupus erythematosus, which is an autoimmune disease that causes inflammation and damage to various organs and tissues in the body.
Choice B reason: Abdominal cramping pain is not the expected finding because it is a symptom that can be caused by various conditions, such as irritable bowel syndrome, appendicitis, or diverticulitis. Abdominal cramping pain is not a specific manifestation of systemic lupus erythematosus, although some clients may experience abdominal discomfort due to gastritis, pancreatitis, or peritonitis, which are possible complications of the disease.
Choice C reason: Whitish patches on the tongue are not the expected finding because they are a sign of oral candidiasis, which is a fungal infection that affects the mouth and throat. Oral candidiasis can be caused by various factors, such as weakened immune system, antibiotic use, or diabetes. Oral candidiasis is not a typical manifestation of systemic lupus erythematosus, although some clients may have oral ulcers, which are painful sores that appear on the lips, gums, or tongue.
Choice D reason: Arthritis with papular rash is the expected finding because it is a characteristic manifestation of systemic lupus erythematosus, which affects the joints and the skin. Arthritis is a condition where the joints are inflamed, causing pain, stiffness, and swelling. Arthritis can affect any joint in the body, but it is more common in the hands, wrists, and knees. Papular rash is a type of skin rash that consists of small, raised bumps that are red or purple. Papular rash can appear on any part of the body, but it is more common on the face, especially on the cheeks and the bridge of the nose. Papular rash is also known as malar rash or butterfly rash, because of its shape and location.
Correct Answer is C
Explanation
Choice A reason: "My feet swell up during the evening." is not a specific statement for systolic heart failure, but a general sign of fluid retention. Fluid retention may occur in both systolic and diastolic heart failure, as well as other conditions such as kidney disease, liver disease, or venous insufficiency.
Choice B reason: "It's harder to breathe during hot and humid weather." is not a specific statement for systolic heart failure, but a common complaint of many people with respiratory problems. Hot and humid weather may increase the workload of the lungs and the heart, but it does not indicate a reduced ejection fraction, which is the hallmark of systolic heart failure.
Choice C reason: "I wake up at night being short of breath." is the best statement for systolic heart failure, as it indicates a condition called paroxysmal nocturnal dyspnea. Paroxysmal nocturnal dyspnea is a sudden onset of breathlessness that occurs during sleep, usually due to fluid accumulation in the lungs. It is a sign of left-sided systolic heart failure, which is a failure of the left ventricle to pump blood effectively to the body.
Choice D reason: "I have stomach pain that is worse after meals." is not a specific statement for systolic heart failure, but a possible symptom of gastrointestinal disorders. Stomach pain may be caused by gastritis, ulcers, gallstones, or pancreatitis, among other conditions. It does not reflect the cardiac function or output, which are impaired in systolic heart failure.
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