Which term describes the inflammatory mediator released during the early phase of type 1 hypersensitivity response causing immediate bronchoconstriction and vasodilation?

Prostaglandins

Histamine

Leukotrienes

Bradykinin

Answer and Explanation

The Correct Answer is B

Choice A reason: Prostaglandins are inflammatory mediators that are derived from arachidonic acid. They are involved in both the early and late phases of type 1 hypersensitivity response, but they do not cause immediate bronchoconstriction and vasodilation. They mainly cause pain, fever, and inflammation.

Choice B reason: Histamine is an inflammatory mediator that is stored in mast cells and basophils. It is released during the early phase of type 1 hypersensitivity response, which occurs within minutes of exposure to an allergen. It causes immediate bronchoconstriction and vasodilation, as well as increased vascular permeability, mucus secretion, and itching.

Choice C reason: Leukotrienes are inflammatory mediators that are derived from arachidonic acid. They are involved in the late phase of type 1 hypersensitivity response, which occurs several hours after exposure to an allergen. They cause sustained bronchoconstriction and inflammation, as well as increased mucus production and airway edema.

Choice D reason: Bradykinin is an inflammatory mediator that is formed from plasma proteins. It is not directly involved in type 1 hypersensitivity response, but it may be activated by the complement system, which is part of the innate immune system. It causes vasodilation, increased vascular permeability, and pain.

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Correct Answer is C

Explanation

Choice A reason: Non-Hodgkin lymphoma is not the correct answer because it is a type of cancer that affects the lymphocytes, which are a type of white blood cell that are part of the immune system. Non-Hodgkin lymphoma does not have Reed-Sternberg cells, which are abnormal, large, and multinucleated cells that are characteristic of Hodgkin lymphoma.

Choice B reason: Multiple myeloma is not the correct answer because it is a type of cancer that affects the plasma cells, which are a type of lymphocyte that produce antibodies. Multiple myeloma does not have Reed-Sternberg cells, but it can have abnormal plasma cells that are called myeloma cells.

Choice C reason: Hodgkin lymphoma is the correct answer because it is a type of cancer that affects the lymphatic system, which is a network of organs, tissues, and vessels that help fight infections and diseases. Hodgkin lymphoma has Reed-Sternberg cells, which are the hallmark of this disease. Reed-Sternberg cells are thought to be derived from B lymphocytes, which are a type of lymphocyte that produce antibodies.

Choice D reason: Acute lymphocytic leukemia is not the correct answer because it is a type of cancer that affects the immature lymphocytes, which are called lymphoblasts. Acute lymphocytic leukemia does not have Reed-Sternberg cells, but it can have abnormal lymphoblasts that are called leukemic cells.

A. Facial muscle atrophy B. Facial and periorbital edema C. Facial muscle twitching D. Unilateral ptosis

Correct Answer is B

Explanation

Choice A reason: Facial muscle atrophy is not the expected finding because it is a condition where the facial muscles lose their mass and strength, which can be caused by various factors, such as aging, nerve damage, or muscular dystrophy. Facial muscle atrophy is not a common manifestation of myxedema, which is a severe form of hypothyroidism, which is a condition where the thyroid gland does not produce enough thyroid hormones, which regulate the metabolism and growth of the body.

Choice B reason: Facial and periorbital edema is the expected finding because it is a characteristic manifestation of myxedema, which is caused by the accumulation of mucopolysaccharides, which are complex carbohydrates that are normally found in the connective tissues. Mucopolysaccharides can attract water and cause swelling of the tissues, especially in the face and around the eyes. Facial and periorbital edema can also cause the facial features to appear coarse and puffy, and the eyelids to droop.

Choice C reason: Facial muscle twitching is not the expected finding because it is a condition where the facial muscles contract involuntarily, which can be caused by various factors, such as stress, fatigue, or caffeine. Facial muscle twitching is not a common manifestation of myxedema, which can cause the facial muscles to become weak and slow, and the facial expressions to become dull and flat.

Choice D reason: Unilateral ptosis is not the expected finding because it is a condition where one eyelid droops lower than the other, which can be caused by various factors, such as nerve damage, stroke, or tumor. Unilateral ptosis is not a common manifestation of myxedema, which can cause bilateral ptosis, which is the drooping of both eyelids, due to the edema and weakness of the eyelid muscles.

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Which term describes the inflammatory mediator released during the early phase of type 1 hypersensitivity response causing immediate bronchoconstriction and vasodilation?

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Correct Answer is B

Explanation

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