Which type of diabetes mellitus is characterized by an autoimmune destruction of pancreatic beta cells, leading to an absolute deficiency of insulin production?

Peripheral arterial disease (PAD) is a chronic complication of diabetes mellitus that results from the thickening and narrowing of small blood vessels, leading to reduced blood flow to the lower extremities. This can cause symptoms such as leg pain, numbness, and poor wound healing.

Incorrect choices:

a. This choice is incorrect. Diabetic ketoacidosis (DKA) is an acute complication characterized by high blood glucose levels, ketosis, and metabolic acidosis.

b. This choice is incorrect. Diabetic nephropathy is a chronic complication that affects the kidneys and can lead to impaired kidney function.

c. This choice is incorrect. Diabetic neuropathy refers to nerve damage due to diabetes and can cause symptoms such as tingling, pain, and loss of sensation in the extremities.

Glipizide is a sulfonylurea medication that stimulates insulin secretion from pancreatic beta cells, helping to lower blood glucose levels in individuals with type 2 diabetes mellitus.

Incorrect choices:

a. This choice is incorrect. Metformin is an oral antidiabetic medication that primarily improves insulin sensitivity and reduces hepatic glucose production.

c. This choice is incorrect. Insulin glargine is a long-acting basal insulin used in insulin therapy to provide consistent background insulin coverage.

d. This choice is incorrect. Acarbose is an alpha-glucosidase inhibitor that delays carbohydrate absorption in the intestines and is used to manage postprandial hyperglycemia.