Which variables can help determine the client's response to a drug? (Select all that apply.)

Liver disease

Gender

Height

Age

Genetic factors

Answer and Explanation

Correct Answer : A,C,D,E

a) Liver disease can affect drug metabolism and clearance, influencing the response to medications.

b) Gender may play a role in drug response, as there are some gender-related differences in drug metabolism and distribution.

c) Height can influence drug dosing, especially for medications with weight-based dosing.

d) Age is a crucial factor in drug response, as the metabolism and elimination of drugs can vary across different age groups.

e) Genetic factors, including variations in drug-metabolizing enzymes and drug receptors, can significantly impact an individual's response to a drug.

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Correct Answer is ["A","B"]

Explanation

A) Hold metformin 24 hours to 48 hours before the CT. This is correct because it reduces the chance of metformin accumulating in the blood and causing lactic acidosis when combined with the contrast dye.

B) Hold metformin 48 hours after the CT. This is also correct because it allows time for the contrast dye to be eliminated from the body before resuming metformin.

C) Double the metformin dose after the CT. This is incorrect and dangerous because it can cause hypoglycemia, low blood sugar, which can lead to confusion, seizures, coma, or death. D) Take metformin as scheduled the day of the CT. This is incorrect and risky because it can result in high levels of metformin in the blood when mixed with the contrast dye, increasing the likelihood of lactic acidosis.

E) Resume metformin at half dose after the CT. This is incorrect and unnecessary because there is no evidence that reducing the dose of metformin after a CT scan with contrast dye has any benefit or reduces any harm.

A. The drug will reduce redness and itching but not edema. B. The client should report nausea while taking the medication. C. The client should avoid drinking alcohol while taking the drug. D. This medication is not likely to cause sedation.

Correct Answer is C

Explanation

A) Hydroxyzine is an antihistamine that can reduce redness, itching, and edema.

B) While nausea can be a side effect, it is not the primary concern with hydroxyzine.

C) Avoiding alcohol is important as it can enhance the sedative effects of hydroxyzine.

D) Hydroxyzine is known for its sedative effects, and sedation is a common side effect that the client should be aware of.

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Which variables can help determine the client's response to a drug? (Select all that apply.)

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The diabetic client is scheduled for a computed tomography (CT) scan with intravenous contrast. What education will the nurse provide? (Select all that apply.)

Correct Answer is ["A","B"]

Explanation

The nurse will include which information when teaching a client about hydroxyzine?

Correct Answer is C

Explanation

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