Which variables can help determine the client's response to a drug? (Select all that apply.)

Liver disease

Gender

Height

Age

Genetic factors

Answer and Explanation

Correct Answer : A,C,D,E

a) Liver disease can affect drug metabolism and clearance, influencing the response to medications.

b) Gender may play a role in drug response, as there are some gender-related differences in drug metabolism and distribution.

c) Height can influence drug dosing, especially for medications with weight-based dosing.

d) Age is a crucial factor in drug response, as the metabolism and elimination of drugs can vary across different age groups.

e) Genetic factors, including variations in drug-metabolizing enzymes and drug receptors, can significantly impact an individual's response to a drug.

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Correct Answer is D

Explanation

a) Amlodipine is a calcium channel blocker and is less likely to cause angioedema compared to ACE inhibitors like captopril.

b) Budesonide is a corticosteroid and is not typically associated with angioedema.

c) Simvastatin is a statin and is not known to cause angioedema.

d) Captopril is an ACE inhibitor, and angioedema is a known adverse effect. In the presence of localized swelling of the lips and tongue, discontinuation of captopril is likely indicated.

A. 30 to 60 minutes before breakfast B. At bedtime C. When they feel fatigued D. With an antacid

Correct Answer is B

Explanation

a) Levothyroxine is usually recommended to be taken 30 to 60 minutes before breakfast to enhance absorption, but this is not the answer indicated by the client's statement.

b) Taking levothyroxine at bedtime is another acceptable option and may be more convenient for some individuals. Both options (morning or bedtime) are valid.

c) Taking levothyroxine when feeling fatigued is not a specific guideline for medication administration.

d) Taking levothyroxine with an antacid may interfere with absorption and is not recommended.

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Which variables can help determine the client's response to a drug? (Select all that apply.)

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client arrives in the emergency department with localized swelling of the lips and tongue. The client's medication list includes the following medications. Which of these medications does the nurse anticipate the provider discontinuing?

Correct Answer is D

Explanation

The nurse reinforces instructions regarding when to take levothyroxine and determines teaching was effective when the client states the medication should be taken in which manner?

Correct Answer is B

Explanation

The diabetic client is scheduled for a computed tomography (CT) scan with intravenous contrast. What education will the nurse provide? (Select all that apply.)

A nurse is talking to a client who wants to stop taking glucocorticoids after taking them for 3 months. Which statement by the client indicates a good understanding of the teaching about withdrawal?

The nurse is obtaining a history from a client who discloses daily use of St. John's Wort in addition to prescription drugs. Which effect of this dietary supplement would most concern the nurse?

A nurse is performing a preoperative drug history on a client who is admitted to the hospital for surgery. To evaluate the risk of hemorrhage, the nurse will ask the client about antiplatelet and anticoagulant medications as well as which dietary supplement?

Which of these situations would cause the nurse to hold a dose of morphine?

A client is starting to take furosemide and asks the nurse. "When is the best time to take this medication?" What is the nurse's response?

An adolescent client is taking a leukotriene blocker. Which of these statements by the client requires the most immediate intervention?

A client with an infection is being treated with vancomycin. The nurse providing care reviews the client's laboratory reports and notes that the client's blood urea nitrogen (BUN) and serum creatinine levels are newly elevated. What would be the appropriate nursing intervention?