Which variables can help determine the client's response to a drug? (Select all that apply.)

Liver disease

Gender

Height

Age

Genetic factors

Answer and Explanation

Correct Answer : A,C,D,E

a) Liver disease can affect drug metabolism and clearance, influencing the response to medications.

b) Gender may play a role in drug response, as there are some gender-related differences in drug metabolism and distribution.

c) Height can influence drug dosing, especially for medications with weight-based dosing.

d) Age is a crucial factor in drug response, as the metabolism and elimination of drugs can vary across different age groups.

e) Genetic factors, including variations in drug-metabolizing enzymes and drug receptors, can significantly impact an individual's response to a drug.

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Correct Answer is B

Explanation

A) Allopurinol inhibits the synthesis of uric acid, preventing its formation.

B) Colchicine is typically used for gout flares and reduces inflammation but is not usually taken concurrently with probenecid and allopurinol. NSAIDs or corticosteroids are often used for pain control during acute attacks.

C) Colchicine is known for its anti-inflammatory properties but does not prevent uric acid synthesis or facilitate its elimination.

D) Probenecid increases the excretion of uric acid in the urine.

A. "I will take this medication with meals to help prevent stomach upset." B. "I may experience tinnitus with higher doses of this medication." C. "I should stop drinking alcohol." D. "I may take up to 1000 mg four times daily for pain."

Correct Answer is B

Explanation

A) Taking ibuprofen with meals is a good practice to reduce the risk of stomach upset.

B) Tinnitus is not a typical side effect of ibuprofen, and this statement may indicate a misunderstanding or confusion with another medication.

C) Stopping alcohol consumption is advisable as it can increase the risk of gastrointestinal bleeding when combined with ibuprofen.

D) The dosing information provided is within the typical recommended range for ibuprofen, and the statement is accurate.

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Which variables can help determine the client's response to a drug? (Select all that apply.)

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client who is suffering from an acute gout attack wants to know how colchicine differs from probenecid and allopurinol in its actions. Which of these statements shows the need for further teaching regarding the purpose and use of these medications?

Correct Answer is B

Explanation

A nurse is providing teaching for an adult client with arthritis who has been instructed to take ibuprofen for discomfort. Which statement by the client indicates a need for further education?

Correct Answer is B

Explanation

A client receiving a cephalosporin has passed six distinct-smelling, unformed stools in the first 6 hours of the nurse's shift. What is the nurse's best action?

A client has had emergency surgery for a ruptured appendix. Before surgery, the client was taking dexamethasone for three years. With the client's steroid use history, for which complication will the nurse monitor in the recovery phase?

The nurse receives an order to give atropine 300mcg SQ now. The medication is available in 1mg/mL vial. How many mL should the nurse administer? (Record the answer to the tenth, or one decimal place. Use a leading zero if it applies. Do not use a trailing zero.)

Which of these findings would cause the nurse to hold the administration of oral metoprolol 25 mg?

When administering medications to infants, it is essential to remember which of the following? (Select all that apply.)

A prescriber has ordered medication for a newborn that is eliminated primarily by hepatic metabolism. What would the nurse expect the prescriber to order?

The nurse is obtaining a history from a client who discloses daily use of St. John's Wort in addition to prescription drugs. Which effect of this dietary supplement would most concern the nurse?