Which variables can help determine the client's response to a drug? (Select all that apply.)
Liver disease
Gender
Height
Age
Genetic factors
Correct Answer : A,C,D,E
a) Liver disease can affect drug metabolism and clearance, influencing the response to medications.
b) Gender may play a role in drug response, as there are some gender-related differences in drug metabolism and distribution.
c) Height can influence drug dosing, especially for medications with weight-based dosing.
d) Age is a crucial factor in drug response, as the metabolism and elimination of drugs can vary across different age groups.
e) Genetic factors, including variations in drug-metabolizing enzymes and drug receptors, can significantly impact an individual's response to a drug.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
a) This statement inaccurately describes the concept of half-life. Half-life refers to the time it takes for the drug concentration in the body to decrease by half, not the time it takes for the drug to reach receptors.
c) This statement inaccurately describes the concept of half-life. Half-life is not related to the distribution of the drug in the body.
d) This statement inaccurately describes the concept of half-life. Half-life is not related to the shelf-life of the drug.
Correct Answer is A
Explanation
A) The nurse should hold the administration of oral metoprolol 25 mg if the blood pressure of the patient is 92/44 mmHg, as this indicates hypotension, which can be worsened by the beta blocker effect of metoprolol.
B) A respiratory rate of 26 breaths per minute is within the acceptable range for administering metoprolol.
C) A heart rate of 92 beats per minute is within the acceptable range for administering metoprolol.
D) Holding the administration of metoprolol may be appropriate if the oxygen saturation level is low. Metoprolol is primarily used for heart rate and blood pressure control and may not be the immediate concern in a client with low oxygen saturation. The healthcare provider should be consulted for further guidance.
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