Which variables can help determine the client's response to a drug? (Select all that apply.)
Liver disease
Gender
Height
Age
Genetic factors
Correct Answer : A,C,D,E
a) Liver disease can affect drug metabolism and clearance, influencing the response to medications.
b) Gender may play a role in drug response, as there are some gender-related differences in drug metabolism and distribution.
c) Height can influence drug dosing, especially for medications with weight-based dosing.
d) Age is a crucial factor in drug response, as the metabolism and elimination of drugs can vary across different age groups.
e) Genetic factors, including variations in drug-metabolizing enzymes and drug receptors, can significantly impact an individual's response to a drug.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
a) An elevated temperature could indicate an infection, which is a serious concern in a client taking steroids, as steroids can suppress the immune system. This finding should be reported immediately.
b) Blood pressure within this range is generally acceptable and may not be a cause for immediate concern.
c) A glucose level of 128 mg/dl is within a reasonable range and may not require immediate reporting unless there are other concerning factors.
d) A heart rate of 102 beats per minute is generally within an acceptable range and may not be an immediate cause for concern in the absence of other symptoms.
Correct Answer is A
Explanation
a) St. John's Wort is known to increase the risk of bleeding, particularly when used in conjunction with anticoagulant medications. This effect is of concern and may require adjustments in the treatment plan.
b) While St. John's Wort can interact with various drugs, increasing the risk of bleeding is a more immediate concern.
c) St. John's Wort does not counteract the effects of CNS depressants; it may actually enhance the effects of these drugs.
d) St. John's Wort is known to induce the metabolism of some drugs, potentially reducing their effectiveness, but the immediate concern is the risk of bleeding.
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