The nurse notices that an order for intravenous gentamicin for a newly admitted client is half of the normal dose usually ordered for an adult. Before calling the provider for confirmation of the order, the nurse reviews the client's history to check for which preexisting condition that could have prompted the adjustment to the normal dose?
Antibiotic resistance
Renal disease
Liver disease
Interpatient variation
The Correct Answer is B
A) Antibiotic resistance is not a reason to adjust the dose of gentamicin.
B) Gentamicin is primarily excreted by the kidneys. In the presence of renal disease, the dose may need to be adjusted to prevent toxicity.
C) Liver disease does not directly impact the metabolism or excretion of gentamicin, so it is not typically a factor in dose adjustment.
D) Interpatient variation alone may not prompt a specific dose adjustment; individual patient factors, especially renal function, are crucial in determining gentamicin dosage.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
a) Checking blood sugar once daily or more is a proactive and accurate self-management practice for individuals with diabetes.
b) Glipizide does not contain sulfa, so having a sulfa allergy is not a contraindication for taking this medication. The client needs clarification on this point.
c) Taking glipizide once daily with breakfast is a reasonable dosing schedule.
d) Having a glass of wine with dinner may be acceptable, but moderation and monitoring for interactions are advisable.
Correct Answer is D
Explanation
a) Increasing the frequency of medication dosing may lead to higher overall exposure and is not necessarily related to hepatic metabolism.
b) Ordering a dose that is higher than an adult dose could result in excessive drug levels, especially in a newborn with immature hepatic function.
c) Discontinuing the drug after one or two treatments may not be necessary if the dose is appropriately adjusted based on hepatic metabolism.
d) Ordering a lower dose is appropriate because hepatic metabolism in newborns is often immature, and lower doses are required to avoid toxicity.
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