Your cancer patient has bone marrow suppression from their chemotherapy treatments, and is scheduled to receive Epoetin Alfa shots 3 times per week. Which of the following lab values would cause you to hold the administration of the medication for safety concerns?

Hgb of less than 11

aPTT of 120 seconds

Hgb of more than 11

PT/INR of 3.5

Answer and Explanation

The Correct Answer is C

A.   Epoetin Alfa is typically used to treat anemia, and it is often indicated when hemoglobin (Hgb) levels are below 11 g/dL. Therefore, if the Hgb is less than 11, it would be appropriate to administer the medication to help increase red blood cell production.
B.   Do not hold. An activated partial thromboplastin time (aPTT) of 120 seconds indicates a prolonged coagulation time, which increases the risk of bleeding. However, Epoetin Alfa does not have a direct impact on coagulation, so this value alone would not warrant holding the medication.
C.   Epoetin Alfa is generally not indicated if the Hgb level is already above 11 g/dL, particularly if there’s a risk of increasing the Hgb above the recommended therapeutic range (often above 12 g/dL). If the Hgb exceeds this level, the medication should be held to prevent complications such as thromboembolic events.
D.   A PT/INR of 3.5 indicates a significantly prolonged prothrombin time, suggesting a high risk of bleeding. However, Epoetin Alfa does not directly cause bleeding.

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Correct Answer is A

Explanation

A. PT (Prothrombin Time) and INR (International Normalized Ratio) are tests primarily used to evaluate blood coagulation and the effectiveness of anticoagulant therapy. While they can provide some insight into a patient's overall health, they are not specific indicators of inflammation.
B. CRP is a protein produced by the liver in response to inflammation. It is a well-established marker for detecting acute inflammation and is commonly used in clinical settings to assess inflammatory conditions.
C. ESR measures how quickly red blood cells settle at the bottom of a test tube. An elevated ESR is a classic indicator of inflammation in the body and is commonly used in diagnosing various inflammatory conditions.
D. Procalcitonin is a biomarker that can indicate bacterial infections and systemic inflammation. It is increasingly used in clinical practice to assess the severity of infection and inflammation, particularly in cases of sepsis.

A. 30 minutes B. 90 minutes C. 15 minutes D. 60 minutes

Correct Answer is C

Explanation

A. This is incorrect because the time limit is shorter than 30 minutes.
B. This is also incorrect. You need to start the transfusion sooner than this timeframe.
C. You should start the transfusion within 15 minutes after the blood product is issued from the blood bank. This guideline is critical to minimize the risk of bacterial growth and ensure the safety of the transfusion.
D. The time limit is shorter than 60 minutes, emphasizing the urgency in starting the transfusion to maintain the integrity of the blood product.

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Your cancer patient has bone marrow suppression from their chemotherapy treatments, and is scheduled to receive Epoetin Alfa shots 3 times per week. Which of the following lab values would cause you to hold the administration of the medication for safety concerns?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following lab tests is NOT commonly ordered to ascertain whether the patient is experiencing large amounts of inflammation?

Correct Answer is A

Explanation

You are planning to transfuse a unit of PRBC's to your patient. You know that when you arrive at the blood bank and they hand you the unit of blood, you have how long to start the transfusion from that time?

Correct Answer is C

Explanation

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