Allergic Reactions and Hypersensitivity
- Allergic reactions are immune-mediated responses to foreign substances (allergens) that can cause mild to severe symptoms depending on the type and severity of the reaction
- Hypersensitivity is an exaggerated or inappropriate allergic reaction that can be classified into four types: type I (anaphylactic), type II (cytotoxic), type III (immune complex), or type IV (delayed)
- Both allergic reactions and hypersensitivity can cause itching, rash, hives, or swelling of the face, lips, tongue, or throat
- Anaphylactic reactions can also cause bronchospasm, laryngeal edema, hypotension, tachycardia, or cardiac arrest
- The treatment for allergic reactions and hypersensitivity includes:
- Stopping the infusion and removing the catheter
- Administering epinephrine, antihistamines, corticosteroids, or other medications as ordered
- Providing oxygen and airway support as needed
- Monitoring vital signs and symptoms closely
- Documenting the incident and notifying the provider
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