A 40-year-old patient with polycystic kidney disease is scheduled to receive a kidney transplant.
When the nurse begins to administer 2 units of leukocyte-poor packed red blood cells to treat a low hemoglobin level, the patient asks why this has been prescribed.
What is the appropriate response from the nurse?
“It will reduce the risk of receiving white blood cells from the donor that could impair the function of your transplanted kidney.”
“All pre-transplant patients receive leukocyte-poor blood because it is better absorbed by the body.”
“It causes fewer blood reactions in pre-transplant patients.”
“It is less likely to cause hemolysis, or destruction of the blood cells, after transfusion.”
The Correct Answer is A
Choice A rationale:
Leukocyte-poor packed red blood cells (LP-PRBCs) have a significantly reduced number of white blood cells (WBCs), also known as leukocytes. This is crucial for pre-transplant patients like the one in the question for several reasons:
Prevention of Alloimmunization: WBCs in blood transfusions carry human leukocyte antigens (HLAs), which are proteins on the surface of cells that play a role in the immune system. Exposure to foreign HLAs can cause the recipient's immune system to develop antibodies against them, a process called alloimmunization. These antibodies can then attack and damage the transplanted kidney, leading to rejection. By reducing the number of WBCs in the transfusion, LP-PRBCs significantly lower the risk of alloimmunization.
Reduced Incidence of Febrile Non-Hemolytic Transfusion Reactions (FNHTRs): FNHTRs are the most common type of transfusion reaction, characterized by fever, chills, and occasionally other symptoms like nausea and vomiting. They are thought to be caused by cytokines released from WBCs in the transfused blood. LP-PRBCs, with their reduced WBC content, have been shown to lower the incidence of FNHTRs.
Potential Benefits for Graft Survival: Some studies have suggested that the use of LP-PRBCs for transfusions may improve long-term graft survival rates in kidney transplant patients, although more research is needed to confirm these findings.
Choice B rationale:
This statement is incorrect. While LP-PRBCs may have some advantages in terms of absorption or utilization, this is not the primary reason for their use in pre-transplant patients. The main goal is to reduce the risk of alloimmunization and other transfusion-related complications.
Choice C rationale:
This statement is partially correct. LP-PRBCs do tend to cause fewer blood reactions, particularly FNHTRs, as explained in the rationale for Choice A. However, this is not the most comprehensive or accurate explanation for their use in pre-transplant patients.
Choice D rationale:
This statement is not directly relevant to the use of LP-PRBCs in pre-transplant patients. While LP-PRBCs may have a lower risk of hemolysis, this is not the primary reason for their use in this specific context.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale:
This statement belongs to the "Request" portion of the SBAR format. It articulates a specific action the nurse wants the healthcare provider to take.
It's not part of the Background because it doesn't provide any historical or contextual information about the patient's condition.
Choice B rationale:
This statement is the correct choice for the "Background" portion of the SBAR format.
It provides essential background information about the patient's recent medical history, specifically the recent hysterectomy.
This information is crucial for the healthcare provider to understand the context of the current situation and make informed decisions about pain management.
Choice C rationale:
This statement provides additional patient information, but it's not the most relevant for the Background section in this context.
The patient's aversion to NSAIDs might be important for medication choices, but it doesn't directly address the current issue of pain management after a hysterectomy.
Choice D rationale:
This statement provides important information about the patient's allergies, but it's not the most relevant for the Background section in this context.
Allergies are crucial for medication safety, but they don't directly address the current issue of pain management or provide context about the patient's recent surgery.
Correct Answer is B
Explanation
Choice A rationale:
A serum sodium level of 134 mEq/L (134 mmol/L) is mildly low, but this level of hyponatremia is not typically associated with significant cognitive impairment.
Symptoms of hyponatremia, such as confusion, lethargy, and seizures, usually occur when sodium levels are 125 mEq/L or lower.
However, it's important to monitor this patient for any changes in cognitive status as hyponatremia can worsen and lead to more severe symptoms.
Choice C rationale:
A patient who underwent an open cholecystectomy two days ago may experience some cognitive impairment due to the effects of anesthesia and pain medications.
However, this type of impairment is usually temporary and resolves within a few days.
It's important to assess for cognitive impairment in this patient, but it is not the most urgent priority.
Choice D rationale:
A 32-year-old patient with a 20-pack-year history of smoking is at risk for cognitive impairment due to the long-term effects of smoking on the brain.
However, this risk is typically not as immediate as the risk of cognitive impairment following a stroke.
It's important to educate this patient about the risks of smoking and encourage smoking cessation, but it is not the most urgent priority in terms of cognitive assessment.
Choice B rationale:
An 88-year-old patient who had a hemorrhagic stroke three days ago is at the highest risk for cognitive impairment among the given options.
Hemorrhagic stroke involves bleeding in the brain, which can damage brain tissue and lead to cognitive deficits.
The risk of cognitive impairment is particularly high in older adults, as they may have less cognitive reserve to compensate for the damage caused by the stroke.
Early assessment and intervention for cognitive impairment are crucial for optimizing recovery and quality of life in stroke patients.
Prompt evaluation for cognitive impairment is essential to identify any deficits and initiate appropriate interventions to support the patient's cognitive function and recovery.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.