A 55-year-old male with a 30-year history of smoking is examined for respiratory disturbance. Examination of his airway (bronchial) reveals that stratified squamous epithelial cells have replaced the normal columnar ciliated cells. This type of cellular adaptation is called:
Hyperplasia
Dysplasia
Metaplasia
Hypertrophy
The Correct Answer is C
Choice A Reason:
Hyperplasia refers to an increase in the number of cells in an organ or tissue, usually resulting in an increase in the size of the organ or tissue. This process is often a response to a stimulus and can be physiological or pathological. However, hyperplasia does not involve the replacement of one cell type with another, as seen in this case.
Choice B Reason:
Dysplasia is characterized by abnormal growth and development of cells within tissues or organs. It often indicates a precancerous condition and involves changes in cell size, shape, and organization. While dysplasia can occur in the respiratory tract, it does not describe the replacement of one type of epithelial cell with another.
Choice C Reason:
This is the correct answer. Metaplasia is the process by which one type of adult cell is replaced by another type of adult cell that is not typical for that tissue. In this case, the normal columnar ciliated cells in the bronchial airway have been replaced by stratified squamous epithelial cells, a common adaptation in response to chronic irritation from smoking.
Choice D Reason:
Hypertrophy refers to an increase in the size of cells, leading to an increase in the size of the affected organ or tissue. This process does not involve a change in cell type, making it an incorrect choice for this scenario.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A Reason:
Vomiting is not a risk factor for a heart attack but rather a symptom that can occur during a heart attack. Risk factors are conditions or behaviors that increase the likelihood of developing a disease. Vomiting can be a sign of various conditions, including gastrointestinal issues or even a heart attack, but it does not contribute to the risk of having a heart attack.
Choice B Reason:
Hypertension, or high blood pressure, is a significant risk factor for heart attacks. It causes the heart to work harder than normal, leading to the thickening of the heart muscle and narrowing of the arteries. Over time, this increased workload can damage the arteries, making them more susceptible to blockages that can cause a heart attack. Managing blood pressure through lifestyle changes and medication is crucial in reducing the risk of heart attacks.
Choice C Reason:
Chest pain is a common symptom of a heart attack but not a risk factor. Risk factors are pre-existing conditions or behaviors that increase the likelihood of developing a disease. Chest pain, also known as angina, occurs when there is reduced blood flow to the heart muscle, often due to blockages in the coronary arteries. While chest pain indicates a potential heart problem, it is not a contributing factor to the development of a heart attack.
Choice D Reason:
Cell necrosis refers to the death of cells, which can occur during a heart attack when the blood supply to part of the heart muscle is blocked. This is a consequence of a heart attack rather than a risk factor. Risk factors are conditions or behaviors that increase the likelihood of developing a disease, whereas cell necrosis is a result of the disease process.
Correct Answer is D
Explanation
Choice A: Minimal Effect on Vessels
A reduction in blood pH, which indicates acidosis, does not have a minimal effect on blood vessels. Acidosis can significantly impact vascular tone and function. Therefore, this choice is incorrect as it underestimates the physiological changes that occur in response to a decrease in pH.
Choice B: No Effect on Vessels
Similarly, stating that a reduction in blood pH has no effect on vessels is inaccurate. Blood pH is tightly regulated, and deviations from the normal range (7.35-7.45) can lead to significant physiological responses. Acidosis can alter vascular tone, making this choice incorrect.
Choice C: Vasodilation
While vasodilation can occur in response to certain conditions, a reduction in blood pH typically leads to vasoconstriction rather than vasodilation. Vasodilation is more commonly associated with an increase in blood pH (alkalosis) or other factors such as increased levels of nitric oxide or prostaglandins.
Choice D: Vasoconstriction
When the pH of blood reduces, indicating acidosis, it often leads to vasoconstriction. This response is mediated by chemoreceptors that detect changes in pH and stimulate the vasomotor center to increase vascular tone. Vasoconstriction helps to maintain blood pressure and ensure adequate perfusion of vital organs during acidosis. Therefore, this is the correct answer.
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