A 55-year-old male with a 30-year history of smoking is examined for respiratory disturbance. Examination of his airway (bronchial) reveals that stratified squamous epithelial cells have replaced the normal columnar ciliated cells. This type of cellular adaptation is called:
Hyperplasia
Dysplasia
Metaplasia
Hypertrophy
The Correct Answer is C
Choice A Reason:
Hyperplasia refers to an increase in the number of cells in an organ or tissue, usually resulting in an increase in the size of the organ or tissue. This process is often a response to a stimulus and can be physiological or pathological. However, hyperplasia does not involve the replacement of one cell type with another, as seen in this case.
Choice B Reason:
Dysplasia is characterized by abnormal growth and development of cells within tissues or organs. It often indicates a precancerous condition and involves changes in cell size, shape, and organization. While dysplasia can occur in the respiratory tract, it does not describe the replacement of one type of epithelial cell with another.
Choice C Reason:
This is the correct answer. Metaplasia is the process by which one type of adult cell is replaced by another type of adult cell that is not typical for that tissue. In this case, the normal columnar ciliated cells in the bronchial airway have been replaced by stratified squamous epithelial cells, a common adaptation in response to chronic irritation from smoking.
Choice D Reason:
Hypertrophy refers to an increase in the size of cells, leading to an increase in the size of the affected organ or tissue. This process does not involve a change in cell type, making it an incorrect choice for this scenario.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A Reason:
Inducer medications do not increase the blood level of newly added medications. Instead, they enhance the activity of enzymes that metabolize drugs, leading to a faster breakdown and lower concentration of the new medication in the bloodstream. This can result in reduced efficacy of the newly added medication.
Choice B Reason:
Inducer medications increase the activity of enzymes, particularly those in the cytochrome P450 family, which are responsible for drug metabolism. This increased enzyme activity accelerates the breakdown of the newly added medication, thereby decreasing its blood level and potentially reducing its therapeutic effect. For example, rifampin is a well-known inducer that can significantly lower the levels of drugs metabolized by CYP3A4.
Choice C Reason:
Inducer medications do not increase the half-life of newly added medications. On the contrary, by enhancing the metabolic activity of enzymes, they typically reduce the half-life of the new medication. This means the drug is broken down and eliminated from the body more quickly.
Choice D Reason:
Inducer medications do have a significant effect on new medications. They alter the metabolism of drugs by increasing the activity of metabolic enzymes, which can lead to decreased blood levels and reduced effectiveness of the new medication. Ignoring this interaction can result in subtherapeutic drug levels and treatment failure.
Correct Answer is C
Explanation
Choice A Reason:
The sympathetic nervous system (SNS) plays a role in regulating body temperature. It does this by controlling the dilation and constriction of blood vessels in the skin, which helps to dissipate or conserve heat as needed. Therefore, the statement that the SNS regulates body temperature is correct.
Choice B Reason:
The SNS is crucial in regulating the cardiovascular system. It increases heart rate and the force of heart contractions, and it also causes vasoconstriction, which raises blood pressure. This statement is accurate and does not indicate a need for further teaching.
Choice C Reason:
This is the correct answer. The SNS generally inhibits digestive functions during the “fight-or-flight” response. It reduces blood flow to the digestive organs, decreases peristalsis, and inhibits digestive secretions. Therefore, the statement that the SNS regulates digestive functions is incorrect and indicates a need for further teaching.
Choice D Reason:
The SNS is responsible for the “fight-or-flight” response, which prepares the body to respond to perceived threats. This includes increasing heart rate, dilating airways, and mobilizing energy stores. This statement is correct and does not indicate a need for further teaching.
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