Which statement regarding alpha 1 and alpha 2 receptors is correct?
Alpha 1 agonist and alpha 2 antagonist increase blood pressure
Alpha 1 agonist and alpha 2 agonist decrease blood pressure
Alpha 1 and alpha 2 agonist increase blood pressure
Alpha 1 antagonist and alpha 2 agonist decrease blood pressure
The Correct Answer is A
Choice A: Alpha 1 Agonist and Alpha 2 Antagonist Increase Blood Pressure
Alpha 1 receptors are primarily located on the smooth muscles of blood vessels. When activated by an agonist, these receptors cause vasoconstriction, which increases blood pressure. On the other hand, alpha 2 receptors are found on presynaptic nerve terminals and act to inhibit the release of norepinephrine. An antagonist at alpha 2 receptors would prevent this inhibition, leading to increased norepinephrine release, further promoting vasoconstriction and increasing blood pressure. Therefore, the combination of an alpha 1 agonist and an alpha 2 antagonist would synergistically increase blood pressure.
Choice B: Alpha 1 Agonist and Alpha 2 Agonist Decrease Blood Pressure
Alpha 1 agonists increase blood pressure by causing vasoconstriction. Alpha 2 agonists, however, decrease blood pressure by inhibiting norepinephrine release, leading to vasodilation. Therefore, this combination would not decrease blood pressure as the effects of the alpha 1 agonist would counteract the effects of the alpha 2 agonist.
Choice C: Alpha 1 and Alpha 2 Agonist Increase Blood Pressure
While alpha 1 agonists increase blood pressure through vasoconstriction, alpha 2 agonists actually decrease blood pressure by reducing norepinephrine release. Therefore, this statement is incorrect as the combined effect would not result in an increase in blood pressure.
Choice D: Alpha 1 Antagonist and Alpha 2 Agonist Decrease Blood Pressure
Alpha 1 antagonists block the vasoconstrictive action of alpha 1 receptors, leading to vasodilation and a decrease in blood pressure. Alpha 2 agonists also decrease blood pressure by inhibiting norepinephrine release. Therefore, this combination would indeed decrease blood pressure, making this statement partially correct but not the best answer compared to choice A.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A: Calcium
Calcium plays a crucial role in various physiological processes, including muscle contraction, blood clotting, and nerve transmission. While calcium is essential for maintaining overall health, it is not directly associated with changes in blood pH. Calcium levels are tightly regulated by hormones such as parathyroid hormone (PTH) and calcitonin, but these do not significantly influence blood pH.
Choice B: Sodium
Sodium is a major extracellular electrolyte that helps regulate fluid balance, nerve function, and muscle contraction. Although sodium is vital for maintaining osmotic balance and blood pressure, it does not directly affect blood pH. Sodium levels are primarily controlled by the kidneys and hormones like aldosterone, which do not have a direct impact on the acid-base balance of the blood.
Choice C: Magnesium
Magnesium is involved in over 300 biochemical reactions in the body, including protein synthesis, muscle and nerve function, and blood glucose control. While magnesium is important for overall health, it does not have a direct role in altering blood pH. Magnesium levels are regulated by the kidneys and are essential for maintaining normal muscle and nerve function, but they do not directly influence the acid-base balance.
Choice D: Potassium
Potassium is a key intracellular electrolyte that plays a significant role in maintaining the acid-base balance of the blood. Changes in potassium levels can affect the pH of the blood. For example, hyperkalemia (high potassium levels) can lead to acidosis, while hypokalemia (low potassium levels) can lead to alkalosis. Potassium helps regulate the hydrogen ion concentration in the blood, which directly impacts the pH. Therefore, potassium is the electrolyte most closely associated with changes in blood pH.
Correct Answer is B
Explanation
Choice A Reason:
Primary prevention involves measures taken to prevent the onset of a disease before it occurs. This includes lifestyle interventions such as a healthy diet, regular physical activity, and vaccinations. Mammograms, however, are not used to prevent breast cancer from occurring but to detect it early.
Choice B Reason:
Secondary prevention aims to detect and address a disease early in its course to prevent progression. Mammograms are a classic example of secondary prevention because they are used to screen for breast cancer in women who do not yet show symptoms2. Early detection through mammograms can lead to earlier treatment, which can significantly improve outcomes and reduce mortality rates.
Choice C Reason:
Disease treatment refers to the direct management of a diagnosed condition. For breast cancer, this could include surgery, chemotherapy, radiation therapy, and other medical interventions. Mammograms are not a treatment but a diagnostic tool used to detect the presence of cancer.
Choice D Reason:
Tertiary prevention focuses on managing and mitigating the complications of an existing disease to prevent further deterioration. For breast cancer, this might involve rehabilitation, ongoing treatment to prevent recurrence, and palliative care. Mammograms are used for early detection, not for managing complications of already diagnosed cancer.
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