A charge nurse is teaching a newly licensed nurse about Rho(D) immune globulin administration. Which of the following should the charge nurse include as an indication for the administration of Rho(D) immune globulin?
Hyperemesis gravidarum
Rh-positive blood test results
Prescription for an amniocentesis
Anemia
The Correct Answer is C
This is because a prescription for an amniocentesis is an indication for the administration of Rho(D) immune globulin (RhIG) to prevent RhD isoimmunization in mothers who are RhD negative¹². RhD isoimmunization is a condition where the mother's immune system produces antibodies against the RhD antigen on the baby's red blood cells, which can cause hemolytic disease of the newborn (HDN)¹². RhIG is a medication that contains antibodies against the RhD antigen, and it works by binding to and destroying any fetal red blood cells that may enter the maternal circulation, preventing the mother from making her own antibodies¹²³. RhIG is usually given to RhD negative mothers during pregnancy and after delivery if the baby is RhD positive¹².
Amniocentesis is a procedure where a needle is inserted into the uterus to obtain a sample of amniotic fluid, which contains fetal cells and other substances⁴. Amniocentesis can be done for various reasons, such as genetic testing, fetal lung maturity assessment, or infection diagnosis⁴. However, amniocentesis also carries a risk of causing bleeding or leakage of amniotic fluid, which can result in fetal-maternal hemorrhage (FMH), where fetal blood cells enter the maternal circulation⁴⁵. FMH can trigger RhD isoimmunization in RhD negative mothers, so they should receive RhIG within 72 hours of the procedure to prevent this complication⁵.
The other options are not correct because:
a) Hyperemesis gravidarum is not an indication for RhIG administration. Hyperemesis gravidarum is a condition where the mother experiences severe nausea and vomiting during pregnancy, which can cause dehydration, electrolyte imbalance, and weight loss. Hyperemesis gravidarum does not affect the blood type or compatibility of the mother and the baby, and does not increase the risk of RhD isoimmunization or HDN.
b) Rh-positive blood test results are not an indication for RhIG administration. Rh-positive blood test results mean that the mother has the RhD antigen on her red blood cells, and therefore she cannot develop antibodies against it¹². Rh-positive mothers do not need RhIG, as they are not at risk of RhD isoimmunization or HDN¹².
d) Anemia is not an indication for RhIG administration. Anemia is a condition where the mother has a low level of hemoglobin or red blood cells, which can cause fatigue, weakness, and shortness of breath. Anemia can have various causes, such as iron deficiency, bleeding, or infection. Anemia does not affect the blood type or compatibility of the mother and the baby, and does not increase the risk of RhD isoimmunization or HDN.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Magnesium sulfate is a medication that is used to prevent seizures in women with preeclampsia, a condition that causes high blood pressure and organ damage during pregnancy. It is given intravenously (through a vein) and can also help lower blood pressure and relax the uterus¹.
Magnesium sulfate can cause various side effects and complications, such as
- Nausea, vomiting, or diarrhea
- Headache, drowsiness, or confusion
- Flushing, sweating, or feeling hot
- Weakness, muscle twitching, or paralysis
- Low blood pressure or slow heart rate
- Difficulty breathing or respiratory depression
- Allergic reaction or anaphylaxis
One of the serious complications of magnesium sulfate is magnesium toxicity, which occurs when the level of magnesium in the blood becomes too high. Magnesium toxicity can affect the nervous system, the muscles, the heart, and the lungs. It can cause severe symptoms, such as:
- Loss of reflexes
- Slurred speech or blurred vision
- Chest pain or cardiac arrest
- Coma or death
Magnesium toxicity can be caused by several factors, such as:
- Overdose of magnesium sulfate
- Impaired kidney function or renal failure
- Dehydration or fluid loss
- Interaction with other medications, such as calcium channel blockers or neuromuscular blockers
One of the signs of magnesium toxicity is decreased urine output. Urine output is a measure of how much urine the kidneys produce and excrete. It reflects the kidney function and hydration status. Normal urine output for adults is about 0.5 to 1 mL/kg/hour. For a 70 kg adult, this would be about 35 to 70 mL/hour².
Decreased urine output can indicate that the kidneys are not working properly and are unable to filter and remove excess magnesium from the blood. This can lead to a buildup of magnesium in the blood and cause magnesium toxicity. Decreased urine output can also indicate that the body is dehydrated and has low blood volume. This can reduce the blood flow to the kidneys and impair their function².
Therefore, the nurse should recognize urine output 20 mL/hr. as an adverse reaction to magnesium sulfate and report it to the provider immediately. The nurse should also monitor the client's vital signs, reflexes, respiratory status, and magnesium level closely and be prepared to administer calcium gluconate as an antidote if needed¹²³.
The other options are not manifestations that the nurse should recognize as adverse reactions to
magnesium sulfate:
- a) Hypertension is not an adverse reaction to magnesium sulfate, but a symptom of preeclampsia. Magnesium sulfate can help lower blood pressure in women with preeclampsia by relaxing the blood vessels and reducing vascular resistance¹³.
- c) Hyperglycemia is not an adverse reaction to magnesium sulfate, but a condition that causes high blood sugar levels. It can be caused by diabetes mellitus, pregnancy-induced diabetes (gestational diabetes), infection, stress, or certain medications. Magnesium sulfate does not affect blood sugar levels directly.
- d) Respiratory rate 16/min is not an adverse reaction to magnesium sulfate, but a normal finding for
respiratory rate in adults. The normal range for respiratory rate in adults is 12 to 20 breaths per minute. The respiratory rate may vary depending on age, activity level, health status, and environmental factors.
Correct Answer is B
Explanation
The correct answer is choice B. Single palmar creases.
Choice A rationale:
Rust-stained urine is typically due to urate crystals and is common in newborns. It usually resolves on its own and is not a cause for concern.
Choice B rationale:
Single palmar creases can be associated with certain genetic conditions, such as Down syndrome. This finding should be reported to the provider for further evaluation.
Choice C rationale:
Subconjunctival hemorrhage is a common finding in newborns due to the pressure changes during delivery. It usually resolves without intervention and is not typically a cause for concern.
Choice D rationale:
Transient circumoral cyanosis is often seen in newborns and can occur when the baby is crying or feeding. It usually resolves on its own and is not typically a cause for concern.
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