A client asks the nurse about the role of diabetes in the development of chronic renal failure. What is the nurse's best response?

A. Incorrect. Antibiotics are generally safe and are not known to be a risk factor for chronic renal failure.

B. Incorrect. Antihypertensive medications are essential for managing high blood pressure and reducing the risk of kidney damage in individuals with hypertension. They are not considered a risk factor for chronic renal failure.

C. Correct. Proton pump inhibitors (PPIs) are commonly used to treat conditions such as acid reflux and peptic ulcers. Prolonged and high-dose use of PPIs has been associated with an increased risk of kidney disease, including acute interstitial nephritis and chronic kidney disease.

D. Incorrect. Antipyretics such as acetaminophen are generally safe when used appropriately and are not considered a risk factor for chronic renal failure.

A. Correct. ACE inhibitors are commonly prescribed to manage hypertension and fluid overload in clients with chronic renal failure. These medications help relax blood vessels, reduce fluid retention, and lower blood pressure.

B. Incorrect. Phosphate binders are prescribed to control phosphate levels, but they do not directly address fluid overload and hypertension.

C. Incorrect. Erythropoietin-stimulating agents (ESA. are used to manage anemia in chronic renal failure and do not specifically address hypertension or fluid overload.

D. Incorrect. Potassium-sparing diuretics may not be the first for managing fluid overload and hypertension in chronic renal failure, especially if the client has elevated potassium levels. ACE inhibitors are a more suitable option in this scenario.

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