A client diagnosed with strep throat requires antibiotics for treatment. With an allergy to penicillin, the nurse understands which medication should be avoided due to cross-sensitivity with penicillin medications?
Macrolides
Sulfonamides
Cephalosporins
Tetracyclines
The Correct Answer is C
A. Macrolides, such as azithromycin and erythromycin, have a low cross-reactivity with penicillin and are typically safe alternatives for those with penicillin allergies.
B. Sulfonamides are not structurally similar to penicillins and generally do not have cross-sensitivity issues with penicillin allergies.
C. Cephalosporins share a similar beta-lactam structure to penicillins, which can result in cross-sensitivity in some individuals with a penicillin allergy. For this reason, they should be avoided or used with caution in these clients.
D. Tetracyclines have a different structure from penicillins and are usually safe for clients with penicillin allergies.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. A high first-pass effect means that a significant amount of the drug is metabolized by the liver before reaching systemic circulation, making oral administration less effective.
B. Morphine with a high first-pass effect will be more effective when administered via non-enteral routes, such as IV or subcutaneous, to bypass the liver's initial metabolism.
C. The first-pass effect does not influence the kidney’s rate of excretion but rather the liver’s initial metabolism of the drug.
D. The liver, not the kidneys, is responsible for the first-pass metabolism, which occurs before the drug reaches systemic circulation when taken orally.
Correct Answer is B
Explanation
A. Chlorpheniramine is a first-generation antihistamine and may cause sedation and other side effects due to its ability to cross the blood-brain barrier.
B. Cetirizine is a second-generation antihistamine that is less likely to cause sedation and is used to relieve symptoms of allergic rhinitis.
C. Montelukast is a leukotriene receptor antagonist, not an antihistamine, and is used for allergic rhinitis and asthma.
D. Diphenhydramine is a first-generation antihistamine known for its sedative effects and is often used for allergies but is not classified as a second-generation antihistamine.
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