A client is prescribed a thiazide diuretic for the management of hypertension.
The nurse plans to assess the client for allergy to?

HDL stands for high-density lipoprotein, which is a type of cholesterol that carries excess cholesterol from other parts of the body to the liver, where it can be removed.

HDL is sometimes called “good” cholesterol because it helps protect against heart disease.Having high HDL levels is not a characteristic of metabolic syndrome, but rather a protective factor.

Metabolic syndrome is a group of conditions that increase the risk of heart disease, stroke, and type 2 diabetes.These conditions include:

• Low HDLs (choice A): Having low levels of HDL cholesterol is a risk factor for metabolic syndrome, as it means there is less “good” cholesterol to remove excess cholesterol from the blood vessels.

• Type II diabetes mellitus (choice B): This is a condition where the body does not use insulin properly, leading to high blood sugar levels.

Insulin is a hormone that helps the cells take up glucose from the blood.

Insulin resistance is a key feature of metabolic syndrome.

• Hypertension (choice C): This means having high blood pressure, which can damage the heart and blood vessels over time.

High blood pressure is often associated with obesity and insulin resistance, which are common in metabolic syndrome.

• Abdominal obesity (choice E): This means having excess fat around the waist and trunk, also known as central or visceral obesity.

This type of fat is more harmful than fat in other parts of the body, as it can release inflammatory substances that affect the metabolism and increase the risk of cardiovascular disease.

• Hyperglycemia (choice F): This means having high blood sugar levels, which can damage the blood vessels and organs over time.

Hyperglycemia can result from insulin resistance or type 2 diabetes, which are both components of metabolic syndrome.

The normal ranges for some of these conditions are:

• HDL cholesterol: more than 40 mg/dL for men and more than 50 mg/dL for women

• Blood pressure: less than 120/80 mmHg

• Blood sugar: less than 100 mg/dL after fasting or less than 140 mg/dL two hours after eating

• Waist circumference: less than 40 inches for men and less than 35 inches for women

Hypokalemia is a condition where the blood potassium level is too low, which can cause muscle weakness, arrhythmias, and other problems. Diuretics are drugs that increase urine output and help remove excess fluid from the body. Some diuretics, such as loop diuretics, also cause potassium loss in the urine.To prevent hypokalemia, a combination of diuretics may be prescribed, such as a loop diuretic with a potassium-sparing diuretic or a thiazide diuretic. These combinations help balance the potassium level while still removing sodium and water.

Choice A is wrong because they are not a part of the initial diuretic therapy.Combination diuretic therapy is usually reserved for patients who have resistant edema or hypertension that does not respond to monotherapy.

Choice C is wrong because they do not boost the blood-pressure-lowering effect of other medications.Diuretics can lower blood pressure by reducing blood volume and relaxing blood vessels, but they are not used to enhance the effect of other antihypertensive drugs.

Choice D is wrong because they do not have fewer side effects when used in a drug combination.Combination diuretic therapy can increase the risk of electrolyte imbalances, such as hyponatremia, hypokalemia, hypomagnesemia, and metabolic alkalosis.It can also cause hypotension, dehydration, and worsening renal function.Therefore, combination diuretic therapy should be used with caution and close monitoring.

Normal ranges for blood potassium level are 3.5 to 5.0 mmol/L or 3.5 to 5.0 mEq/L.Normal ranges for blood sodium level are 135 to 145 mmol/L or 135 to 145 mEq/L.

Normal ranges for blood pressure are less than 120/80 mm Hg for normal, 120-129/less than 80 mm Hg for elevated, 130-139/80-89 mm Hg for stage 1 hypertension, and 140 or higher/90 or higher mm Hg for stage 2 hypertension.