A client with osteoarthritis presents with joint pain that worsens with weight-bearing activities and improves with rest. Which of the following clinical manifestations is described?
Nocturnal joint pain
Morning joint stiffness lasting for 1 hour
Pain relief with activity
Joint pain that is constant throughout the day
Joint pain that is constant throughout the day
The Correct Answer is C
Pain that worsens with weight-bearing activities and improves with rest is a classic clinical manifestation of osteoarthritis. Activity-related pain is due to the increased stress on the affected joint during movement, while rest allows for decreased pressure and relief of pain.
a. Nocturnal joint pain is more typical of inflammatory arthritis conditions like rheumatoid arthritis, not osteoarthritis.
b. Morning joint stiffness lasting for 1 hour is characteristic of inflammatory arthritis conditions like rheumatoid arthritis, not osteoarthritis.
d. Joint pain that is constant throughout the day may be seen in various joint disorders, but the pattern of pain relief with activity is more indicative of osteoarthritis.
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Correct Answer is B
Explanation
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed for the initial management of osteoarthritis. It helps reduce pain and inflammation in the affected joints. Methotrexate, prednisone, and infliximab are medications used to manage inflammatory arthritis conditions, such as rheumatoid arthritis, and are not typically prescribed for osteoarthritis.
a. Methotrexate is used in the management of inflammatory arthritis conditions, such as rheumatoid arthritis, and is not typically prescribed for osteoarthritis.
c. Prednisone is a corticosteroid used to manage inflammatory arthritis conditions, such as rheumatoid arthritis, and is not typically prescribed for osteoarthritis.
d. Infliximab is a biologic medication used in the management of inflammatory arthritis conditions, such as rheumatoid arthritis, and is not typically prescribed for osteoarthritis.
Correct Answer is D
Explanation
Excessive physical activity and joint overuse can contribute to the development of osteoarthritis. Repetitive use and mechanical stress on the joints can lead to cartilage degeneration over time.
a. Osteoarthritis is primarily a non-inflammatory condition. Chronic inflammation of the synovial membrane is more characteristic of other types of arthritis, such as rheumatoid arthritis.
b. Osteoarthritis is not related to hyperactivity of the immune system. It is not an autoimmune disease, and the immune system is not involved in its pathogenesis.
c. Collagen is an essential component of joint cartilage. A deficiency of collagen would weaken the cartilage and contribute to joint degeneration. However, osteoarthritis is not primarily caused by collagen deficiency.
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