A client with suspected leukemia is undergoing a cytogenetic analysis. What is the primary goal of this test in the diagnostic evaluation of leukemia?
Assess the client's immune response
Determine the client's blood type
Identify specific genetic abnormalities in the leukemic cells
Evaluate the client's liver function
The Correct Answer is C
A) This choice is incorrect because a cytogenetic analysis is not primarily used to assess the client's immune response.
B) This choice is incorrect because determining the client's blood type is not the primary goal of a cytogenetic analysis in the diagnostic evaluation of leukemia.
C) This choice is correct. Cytogenetic analysis is a laboratory test that identifies specific genetic abnormalities, such as chromosomal rearrangements, deletions, or mutations, in the leukemic cells. These genetic findings are essential for diagnosing specific types of leukemia, determining prognosis, and guiding treatment decisions.
D) This choice is incorrect because evaluating the client's liver function is not the primary goal of a cytogenetic analysis in the diagnostic evaluation of leukemia.
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Correct Answer is D
Explanation
A) This choice is incorrect because leukemia arises from the uncontrolled growth and division of abnormal blood cells, not normal blood cells. These abnormal cells disrupt the normal functioning of the blood and bone marrow.
B) This choice is incorrect because while cancerous cells may infiltrate and replace healthy tissues in other types of cancer, leukemia primarily affects the bone marrow and blood, not other organs like the liver and lungs.
C) This choice is incorrect because while leukemia does involve genetic mutations, the formation of abnormal blood cells primarily occurs within the bone marrow, not in the lymph nodes.
D) This choice is correct. The pathophysiology of leukemia involves the abnormal proliferation and differentiation of bone marrow stem cells. These cells undergo genetic mutations, leading to the development of leukemia and the production of abnormal blood cells.
Correct Answer is ["B","C","D","E"]
Explanation
A) This choice is incorrect because unexplained weight gain is not a common symptom of leukemia. Weight loss may be more typical in some cases.
B) This choice is correct. Easy bruising and bleeding are common manifestations of leukemia due to a decreased number of healthy blood cells and platelets, which are responsible for clotting.
C) This choice is correct. Persistent fatigue and weakness are common symptoms of leukemia. Leukemia can lead to a decrease in normal blood cells, causing anemia and leading to fatigue and weakness.
D) This choice is correct. Leukemia can weaken the immune system, making the person more susceptible to infections, leading to frequent infections and fever.
E) This choice is correct. Leukemia can cause the enlargement of lymph nodes, leading to painful and swollen lymph nodes.
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