A drug that is a fifth-generation cephalosporin which is the first in its class effective against MRSA is:
Ceftaroline (Teflaro)
Cefepime (Maxipime)
Ceftriaxone (Rocephin)
Cephalexin (Keflex)
The Correct Answer is A
A. Ceftaroline (Teflaro) is a fifth-generation cephalosporin antibiotic that is effective against MRSA (Methicillin-Resistant Staphylococcus Aureus). It's the first cephalosporin in its class with this capability, making it a valuable choice in treating MRSA infections.
B. Cefepime (Maxipime) is a fourth-generation cephalosporin that does not have specific activity against MRSA.
C. Ceftriaxone (Rocephin) is a third-generation cephalosporin, effective against a wide range of bacteria, but not specifically targeted at MRSA.
D. Cephalexin (Keflex) is a first-generation cephalosporin, primarily effective against Gram-positive bacteria, but not effective against MRSA.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Vancomycin is often administered over at least 60 minutes to reduce the risk of infusion-related reactions, such as "Red Man Syndrome," which is characterized by flushing, rash, and itching. This reaction is caused by the rapid infusion of vancomycin, leading to the release of histamine.
Correct Answer is D
Explanation
Allergic reaction: An allergic reaction can manifest in various ways, including rash, itching, and difficulty breathing. However, the specific symptoms described, along with the context of vancomycin administration, point to red man syndrome in this case.
Rhabdomyolysis: Rhabdomyolysis is a condition where damaged muscle tissue breaks down and releases a protein called myoglobin into the bloodstream. This can cause kidney damage, but the symptoms described do not align with rhabdomyolysis.
Stevens-Johnson syndrome: Stevens-Johnson syndrome is a severe skin reaction that can cause skin and mucous membranes to blister, peel, and can be life-threatening. While it can present with rash and other skin symptoms, the symptoms mentioned in the scenario are more characteristic of red man syndrome.
Red man syndrome: As mentioned earlier, red man syndrome is an allergic reaction to vancomycin characterized by flushing, rash, pruritus, and urticaria (hives), along with rapid heart rate and low blood pressure. It is specific to vancomycin and can be prevented or minimized by slowing down the infusion rate and administering antihistamines.
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