"My doctor said I have an autoimmune disease. What does that mean?" asks a client. How should the nurse respond?

A. Type IV Hypersensitivity (Delayed Hypersensitivity Reaction): This type of reaction involves a delayed immune response, typically occurring 24 to 72 hours after exposure to an antigen. It's characterized by the activation of T cells and macrophages, leading to inflammation. This type of hypersensitivity is often associated with conditions like contact dermatitis and some autoimmune diseases.

B. Type III Hypersensitivity (Antibody-Mediated Reaction): Type III hypersensitivity reactions occur when immune complexes, which are composed of antigens and antibodies, deposit in various tissues. This leads to inflammation and tissue damage. Systemic lupus erythematosus (SLE) is an example of a disease associated with Type III hypersensitivity.

C. Type II Hypersensitivity: This type of reaction involves antibodies (IgG or IgM) targeting antigens on the surface of cells. This can lead to cell destruction through various mechanisms, such as complement activation or antibody-dependent cell-mediated cytotoxicity (ADCC). Examples include hemolytic transfusion reactions and autoimmune hemolytic anemia.

D. Type I Hypersensitivity (Immediate Hypersensitivity Reaction): Type I hypersensitivity is characterized by an immediate immune response, typically occurring within minutes of exposure to an allergen. It involves the release of histamines and other mediators from mast cells and basophils, leading to symptoms like hives, respiratory distress, and anaphylaxis. Allergies, like hay fever and food allergies, are examples of Type I hypersensitivity reactions.

A. Obtaining all cultures before the antibiotic is administered: While obtaining cultures is important for identifying the specific pathogen causing the infection and guiding targeted antibiotic therapy, waiting for culture results can take time. During this time, the infection can progress. Therefore, it's generally recommended to initiate broad-spectrum antibiotics first and then adjust the treatment based on culture results.

B. Delaying administration of the antibiotic until the culture results are available: Delaying antibiotics until culture results are available can be risky, as it allows the infection to progress, potentially leading to sepsis or other severe complications.

C. Administering antipyretics as soon as possible: Administering antipyretics like acetaminophen or ibuprofen can help reduce fever and make the patient more comfortable. However, the primary intervention for a suspected infection is antibiotic therapy, as it targets the underlying cause of the fever.

D. Administering the antibiotic immediately: When dealing with a patient with a fever of unknown origin and a suspected infection, the priority is to start appropriate antibiotic therapy promptly. Delaying antibiotic administration can allow the infection to worsen, leading to serious complications.