A nurse is administering a daily dose of vancomycin at 10:00 AM. At which time should the nurse obtain the patient's blood sample to determine the trough level?

A. Reddened tongue and gums: This side effect is not typically associated with ampicillin. However, certain medications or medical conditions can cause changes in oral tissues, leading to redness in the tongue and gums.

B. Digit numbness and tingling: Ampicillin does not commonly cause numbness and tingling in the fingers and toes. These symptoms can be associated with neurological issues or circulatory problems.

C. Bruising and petechiae: These symptoms can indicate bleeding disorders or low platelet count and are not usually caused by ampicillin. It's essential to investigate further if a patient experiences unexplained bruising or petechiae.

D. Skin rash and loose stools: Skin rash is a known side effect of penicillin-type antibiotics, including ampicillin. Loose stools or diarrhea can also occur due to disruption of the gut flora caused by the antibiotic. Patients should be aware of these possibilities and report any severe or persistent symptoms to their healthcare provider.

A. Dermatitis and headaches: Prednisone use can sometimes cause skin issues, but dermatitis is not a common side effect. Headaches can also occur, but they are not specific to long-term prednisone therapy.

B. Heart failure and headaches: Prednisone does not directly cause heart failure. Headaches can occur but are not specific indicators of prednisone side effects.

C. Hyperglycemia and osteoporosis: Prednisone can lead to elevated blood glucose levels (hyperglycemia) and increased bone loss (osteoporosis) when used long-term. Regular monitoring is essential to manage these potential side effects.

D. Weight loss and hypoglycemia: Prednisone can cause weight gain rather than weight loss. Hypoglycemia (low blood sugar) is not a common side effect of prednisone; it typically causes hyperglycemia (high blood sugar) instead.