A nurse is assisting with the preparation of an educational program about the use of oral contraceptives. The nurse should include that which of the following herbal supplements reduces the effectiveness of oral contraceptives?
Ginger root
St. John's wort
Gingko biloba
Glucosamine
The Correct Answer is B
A. Ginger root is not known to reduce the effectiveness of oral contraceptives significantly.
B. St. John's wort is an herbal supplement that can induce the cytochrome P450 enzyme system, leading to increased metabolism of oral contraceptives and potentially reducing their effectiveness. Women taking oral contraceptives should be cautioned against using St. John's wort or advised to use alternative contraceptive methods.
C. Gingko biloba is not known to reduce the effectiveness of oral contraceptives significantly.
D. Glucosamine is not known to reduce the effectiveness of oral contraceptives significantly.
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Related Questions
Correct Answer is B
Explanation
A. Ginger root is not known to reduce the effectiveness of oral contraceptives significantly.
B. St. John's wort is an herbal supplement that can induce the cytochrome P450 enzyme system, leading to increased metabolism of oral contraceptives and potentially reducing their effectiveness. Women taking oral contraceptives should be cautioned against using St. John's wort or advised to use alternative contraceptive methods.
C. Gingko biloba is not known to reduce the effectiveness of oral contraceptives significantly.
D. Glucosamine is not known to reduce the effectiveness of oral contraceptives significantly.
Correct Answer is C
Explanation
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
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