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A nurse is caring for a 54-year-old male client who has been admitted to the hospital for peptic ulcer disease. The client will begin a long-term regimen of omeprazole (Prilosec). The nurse understands that the patient will be at high risk for developing which of the following complications? (Select All That Apply.)

A.

Osteoporosis and fractures

B.

Torsades de Pointes

C.

Nausea

D.

Rebound acid hypersecretion

Answer and Explanation

Correct Answer : A,D

A. Long-term use of omeprazole is associated with an increased risk of osteoporosis and fractures due to decreased calcium absorption caused by reduced stomach acid. This complication is significant in older adults, particularly with prolonged therapy. 

B. Torsades de Pointes is not a common complication of omeprazole. QT prolongation is more often linked to medications like ondansetron or antiarrhythmics. 

C. Nausea is not a typical complication of omeprazole; rather, it is a symptom the drug may help alleviate as part of managing gastrointestinal conditions. 

D. Rebound acid hypersecretion can occur after discontinuation of omeprazole. The body may produce an excessive amount of acid to compensate for the previous suppression, leading to worsening symptoms if the medication is abruptly stopped. 


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Related Questions

Correct Answer is A

Explanation

A. Lipohypertrophy – This is correct. Lipohypertrophy is the thickening of subcutaneous fat that can occur from repeated insulin injections at the same site. This can interfere with insulin absorption, leading to inconsistent glucose control. Rotating injection sites prevents this complication and ensures even absorption of insulin.

B. Injection pain – This is incorrect. Injection pain is typically related to technique or needle size rather than the location. Rotating injection sites does not specifically address this issue.

C. Rapid absorption – This is incorrect. Rotating injection sites does not necessarily prevent rapid absorption but ensures more consistent absorption rates.

D. Intradermal injection – This is incorrect. Intradermal injection occurs when the needle is not inserted deep enough, unrelated to rotating injection sites.

Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"C"}

Explanation

  • Lispro (Humalog): This is a rapid-acting insulin with an onset of action of 15 to 30 minutes, making it effective for controlling blood sugar spikes after meals.
  • Glargine: This is a long-acting insulin that provides a steady level of insulin over 24 hours, helping to maintain baseline blood glucose levels.

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