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A nurse is caring for a 54-year-old male client who has been admitted to the hospital for peptic ulcer disease. The client will begin a long-term regimen of omeprazole (Prilosec). The nurse understands that the patient will be at high risk for developing which of the following complications? (Select All That Apply.)

A.

Osteoporosis and fractures

B.

Torsades de Pointes

C.

Nausea

D.

Rebound acid hypersecretion

Answer and Explanation

Correct Answer : A,D

A. Long-term use of omeprazole is associated with an increased risk of osteoporosis and fractures due to decreased calcium absorption caused by reduced stomach acid. This complication is significant in older adults, particularly with prolonged therapy. 

B. Torsades de Pointes is not a common complication of omeprazole. QT prolongation is more often linked to medications like ondansetron or antiarrhythmics. 

C. Nausea is not a typical complication of omeprazole; rather, it is a symptom the drug may help alleviate as part of managing gastrointestinal conditions. 

D. Rebound acid hypersecretion can occur after discontinuation of omeprazole. The body may produce an excessive amount of acid to compensate for the previous suppression, leading to worsening symptoms if the medication is abruptly stopped. 


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Related Questions

Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"C"}

Explanation

  • Docusate sodium: This is a surfactant laxative that helps soften stools by allowing water and fats to penetrate the stool, making it easier to pass.
  • Loperamide: This medication is an anti-diarrheal agent that works by slowing down gut movement, which helps reduce the frequency of diarrhea.

Correct Answer is A

Explanation

A. Hyperglycemia: While metformin is used to manage blood glucose levels in clients with diabetes, its interaction with contrast dye does not directly lead to hyperglycemia. However, the risk for kidney injury, which can affect glucose regulation, is a concern.

B. Acute renal failure: This is correct. The combination of metformin and iodine-containing contrast dye increases the risk of acute renal failure, also known as contrast-induced nephropathy (CIN). This occurs because contrast agents can cause kidney damage, and metformin is excreted by the kidneys. If renal function is impaired, the buildup of metformin can lead to lactic acidosis.

C. Acute pancreatitis: While acute pancreatitis is a possible side effect of metformin in some individuals, the primary concern with iodine-containing contrast dye is renal failure, not pancreatitis.

D. Acute liver failure: Metformin is primarily metabolized by the kidneys, not the liver, and does not commonly cause liver failure. Renal failure is the more pressing concern with the use of contrast dye in clients taking metformin.

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