A nurse is caring for a client who has a new prescription of phenelzine (Nardil) for the treatment of depression. Which of the following indicates that the client has developed an adverse effect of this medication?
Hearing loss
Orthostatic hypotension
Weight loss
Gastrointestinal bleeding
The Correct Answer is B
A. Hearing loss is not a common adverse effect of phenelzine (Nardil).
B. Orthostatic hypotension is a common adverse effect of phenelzine due to its monoamine oxidase inhibitor (MAOI) activity, leading to decreased blood pressure upon standing.
C. Weight loss is not a common adverse effect of phenelzine and may be more indicative of other factors or conditions.
D. Gastrointestinal bleeding is not a common adverse effect of phenelzine.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Hearing loss is not a common adverse effect of phenelzine (Nardil).
B. Orthostatic hypotension is a common adverse effect of phenelzine due to its monoamine oxidase inhibitor (MAOI) activity, leading to decreased blood pressure upon standing.
C. Weight loss is not a common adverse effect of phenelzine and may be more indicative of other factors or conditions.
D. Gastrointestinal bleeding is not a common adverse effect of phenelzine.
Correct Answer is C
Explanation
A. GABA (gamma-aminobutyric acid) is not typically targeted by antidepressants.
B. While some antidepressants may indirectly affect epinephrine and norepinephrine levels, the primary mechanism of action for most antidepressants is through increasing levels of serotonin and/or norepinephrine.
C. Antidepressants commonly work by increasing the levels of neurotransmitters such as norepinephrine and serotonin in the brain.
D. The reticular formation is not directly involved in the mechanism of action of antidepressants.
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