Which of the following drug classes does isosorbide (Isordil) belong to?
Beta blockers
Nitrates
Calcium channel blockers
Glycoprotein lib/lla receptor antagonists
The Correct Answer is B
Explanation:
A. Beta blockers are used to manage blood pressure and heart rate but are a different class.
B. Isosorbide is a nitrate, which is used primarily to treat and prevent episodes of angina by relaxing and widening blood vessels.
C. Calcium channel blockers also manage blood pressure and chest pain but act through a different mechanism.
D. Glycoprotein IIb/IIIa receptor antagonists are used to prevent platelet aggregation and are typically used in acute coronary syndrome, not as a long-term treatment for angina.
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Related Questions
Correct Answer is D
Explanation
A. Organic nitrates, such as nitroglycerin, dilate (widen) veins and coronary arteries, leading to decreased preload and afterload, which helps relieve angina pain.
B. Constricting veins and coronary arteries would exacerbate angina symptoms by reducing blood flow to the heart muscle.
C. Dissolving veins and coronary arteries is not a mechanism of action for organic nitrates in the treatment of angina.
D. Dilating veins and coronary arteries is the primary mechanism of action for organic nitrates, resulting in increased blood flow to the heart muscle and relief of angina pain.
Correct Answer is C
Explanation
A. Placing three tablets under the tongue at once is not the recommended initial dosing for nitroglycerin.
B. Nitroglycerin tablets should not be swallowed; they are meant to be taken sublingually (under the tongue) for quick absorption.
C. This is the correct instruction, reflecting the standard protocol for acute angina treatment with nitroglycerin: one tablet under the tongue every 5 minutes as needed, with no more than three tablets in 15 minutes. If pain persists, it is advised to call emergency services.
D. This instruction is inappropriate as it delays immediate treatment for chest pain, which can be critical in the event of acute angina or a heart attack.
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