A nurse is caring for a client who is diagnosed with schizophrenia. Which of the following manifestations should the nurse identify as a negative symptom?

A. One of the most significant potential side effects of clozapine is agranulocytosis, a severe decrease in the number of white blood cells not red blood cells, particularly neutrophils.

B. Limiting fluid intake is not typically a specific concern associated with clozapine.

C. Clozapine is not known to have significant interactions with tyramine-rich foods

D. Medication adherence is a key component in clients on clozapine to prevent acute psychotic episodes.

A. Neonatal abstinence syndrome (NAS) occurs in newborns who have been exposed to opioids or other addictive substances while in the womb, typically due to maternal substance use during pregnancy.

B. The term "substance use disorder" typically refers to the condition in the person who is using the substance, rather than the manifestations experienced by the newborn.

C. Fetal alcohol syndrome (FAS) occurs in infants born to mothers who consumed alcohol during pregnancy. It is characterized by a range of physical, cognitive, and behavioral abnormalities, including growth deficiencies, facial abnormalities, and intellectual disabilities.

D. Tolerance refers to the body's decreased response to a substance due to repeated exposure. While tolerance can develop in both the mother and the fetus when opioids are used during pregnancy, the manifestations observed in the newborn, such as irritability, tremors, and feeding difficulties, are not indicative of tolerance.