A nurse is caring for a client who is starting a course of gentamicin IV for a bacterial infection. Which of the following is the correct expected pharmacological action for this medication?

This medication blocks COX-I and COX-2 enzymes.

This medication reduces the production of angiotensin Il by blocking the conversion of angiotensin I to angiotensin Il and increases levels of bradykinin.

This medication is bactericidal antibiotic that destroys microorganisms by disrupting protein synthesis.

This medication blocks the action of angiotensin ll. which results in vasodilation and excretion of sodium and water.

Answer and Explanation

The Correct Answer is C

A. Incorrect: COX-1 and COX-2 enzyme inhibition is the mechanism of NSAIDs (e.g., ibuprofen), not gentamicin.

B. Incorrect: This describes the mechanism of ACE inhibitors (e.g., enalapril), not gentamicin.

C. Correct: Gentamicin is an aminoglycoside antibiotic that inhibits bacterial protein synthesis, leading to bacterial cell death.

D. Incorrect: This describes the action of angiotensin II receptor blockers (ARBs), not gentamicin.

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Correct Answer is ["B","D"]

Explanation

A. Incorrect: Prophylactic antibiotics are not given for a diagnosed respiratory infection. Instead, targeted treatment based on the pathogen is used.

B. Correct: Clients with prosthetic heart valves need prophylactic antibiotics before dental procedures to prevent infective endocarditis.

C. Incorrect: Upper respiratory infections are often viral, and antibiotics are not routinely needed.

D. Correct: Clients undergoing orthopedic surgery may require prophylactic antibiotics to prevent surgical site infections.

A. 1130 B. 1100 C. 1000 D. 1030

Correct Answer is D

Explanation

A. Incorrect: 1130 is too late for an accurate peak level.

B. Incorrect: 1100 is later than necessary for a peak level.

C. Incorrect: 1000 is when the infusion ends, but the drug has not yet reached peak levels in the blood.

D. Correct: Gentamicin peak levels are typically measured 30 minutes after the infusion is completed. Since the infusion starts at 0900 and runs for 60 minutes (until 1000), the peak level should be drawn at 1030.

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A nurse is caring for a client who is starting a course of gentamicin IV for a bacterial infection. Which of the following is the correct expected pharmacological action for this medication?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is teaching a group of nurses about the importance of prophylactic antimicrobial therapy. Which information should the primary nurse include in the teaching? (Select All That Apply).

Correct Answer is ["B","D"]

Explanation

A nurse is administering gentamicin by intravenous (IV) route at 0900. The medication will take 60 minutes to infuse. When should the nurse obtain a blood sample for a peak blood level of gentamicin?

Correct Answer is D

Explanation

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