A nurse is caring for a client who is taking acetaminophen (Tylenol) at regular intervals for mild pain. The nurse should tell the client to report which of the following early manifestations of acetaminophen toxicity?

A. Morphine sulfate is an opioid used for pain management and not for treating opioid use disorder.
B. Fentanyl is a powerful opioid and would not be prescribed for opioid abuse; it may be used for pain management in certain cases but is not for detoxification or maintenance.
C. Naltrexone is another option for opioid use disorder but is typically used after detoxification. It is not used for detoxification itself.
D. Methadone is commonly prescribed for the treatment of opioid use disorder, as it helps reduce cravings and withdrawal symptoms without causing a high.

A. Agitation is not a typical complication of morphine sulfate. In fact, morphine and other opioids generally cause sedation rather than agitation. Agitation may occur in rare cases due to discomfort (such as from constipation) or withdrawal symptoms, but it is not a common complication of morphine use.
B. Respiratory depression is a known and serious complication of morphine sulfate and other opioid medications. Opioids can reduce the body's respiratory drive, leading to slower and less effective breathing. This can be life-threatening, especially with higher doses or if combined with other sedative medications.
C. Dilated pupils (mydriasis) are typically not a complication of morphine use. Opioids, including morphine, typically cause constricted pupils (miosis), which is a hallmark sign of opioid use or overdose. Dilated pupils are more commonly associated with stimulant drug use (e.g., cocaine) or certain medical conditions, not opioids like morphine.
D. Bradycardia (slow heart rate) is a known side effect of morphine sulfate and other opioids. Opioids can affect the autonomic nervous system and cause a decrease in heart rate. This is particularly important to monitor for, especially in patients with existing heart conditions or those taking other medications that might also affect heart rate.
E. Diarrhea is generally not a complication of morphine use. Instead, one of the most common side effects of morphine and other opioids is constipation due to their effect on the gastrointestinal system. Opioids slow down the movement of the intestines, which can lead to constipation, but diarrhea is not a typical response.