A nurse is providing an in-service regarding medications that can cause abstinence syndrome. Which of the following medications can cause abstinence syndrome? (Select All That Apply.).
Butorphanol (Stadol)
Buprenorphine (Buprenex)
Oxycodone (Oxycontin)
Naloxone (Narcan)
Correct Answer : A,B
A. Butorphanol is a mixed opioid agonist-antagonist that can cause withdrawal symptoms in opioid- dependent clients due to its partial antagonism at mu receptors.
B. Buprenorphine is a partial agonist at mu receptors and can also precipitate withdrawal symptoms in individuals who are opioid-dependent.
C. Oxycodone is a full agonist and does not cause withdrawal symptoms unless abruptly discontinued in opioid-dependent individuals.
D. Naloxone is an opioid antagonist used to reverse opioid overdose and is unlikely to cause abstinence syndrome, although it can precipitate withdrawal in opioid-dependent clients when used.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B"]
Explanation
A. Butorphanol is a mixed opioid agonist-antagonist that can cause withdrawal symptoms in opioid- dependent clients due to its partial antagonism at mu receptors.
B. Buprenorphine is a partial agonist at mu receptors and can also precipitate withdrawal symptoms in individuals who are opioid-dependent.
C. Oxycodone is a full agonist and does not cause withdrawal symptoms unless abruptly discontinued in opioid-dependent individuals.
D. Naloxone is an opioid antagonist used to reverse opioid overdose and is unlikely to cause abstinence syndrome, although it can precipitate withdrawal in opioid-dependent clients when used.
Correct Answer is D
Explanation
A. Ibuprofen does not inhibit mu receptors. Mu receptors are associated with opioid actions, while ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).
B. While long-term use of ibuprofen may increase the risk of cardiovascular events like myocardial infarction, this is not the primary action of the drug.
C. Ibuprofen does not decrease the risk of stroke. In fact, chronic use of NSAIDs may actually increase the risk of bleeding and stroke.
D. Ibuprofen inhibits both COX-1 and COX-2 enzymes, which are involved in the inflammatory process. This inhibition helps reduce pain, inflammation, and fever.
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