A nurse is preparing to administer naloxone (Narcan). The nurse understands that this medication has a rapid first-pass inactivation. Which of the route should the nurse NOT administer this medication?
Subcutaneous (SQ)
Intravenous (IV)
Oral (PO)
Intramuscular (IM)
The Correct Answer is C
A. Subcutaneous administration is an acceptable route for naloxone when IV access is not available.
B. Intravenous administration is an effective route for naloxone, especially in emergency situations where rapid action is needed.
D. Intramuscular administration is also effective and commonly used, especially in opioid overdose situations.
C. Naloxone should not be administered orally because it undergoes rapid first-pass metabolism in the liver, which would significantly reduce its effectiveness.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Subcutaneous administration is an acceptable route for naloxone when IV access is not available.
B. Intravenous administration is an effective route for naloxone, especially in emergency situations where rapid action is needed.
D. Intramuscular administration is also effective and commonly used, especially in opioid overdose situations.
C. Naloxone should not be administered orally because it undergoes rapid first-pass metabolism in the liver, which would significantly reduce its effectiveness.
Correct Answer is C
Explanation
A. Indigestion is not a severe side effect, although it can be uncomfortable; it is not an indication to stop the medication.
B. Weight gain is not a common or serious adverse effect of sumatriptan.
C. Persistent chest pain is a serious adverse effect of sumatriptan, as it can indicate a cardiovascular event such as angina or a heart attack. The client should stop taking the medication and seek immediate medical attention.
D. Nausea may occur with sumatriptan use but is not a serious adverse effect unless it is accompanied by other severe symptoms.
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