A nurse is caring for a pre-term newborn who has a patent ductus arteriosus (PDA).

Which of the following medications should the nurse expect to administer to close the ductus arteriosus?

Betamethasone is a corticosteroid that is given to pregnant women who are at risk of preterm delivery to enhance fetal lung maturity and prevent respiratory distress syndrome.It is usually given in two doses, 24 hours apart, and takes effect within 24 hours of administration.

Choice B.Magnesium sulfate is wrong because it is used to prevent seizures in women with severe preeclampsia or eclampsia, not to prevent respiratory distress syndrome.

Choice C.Nifedipine is wrong because it is a calcium channel blocker that is used to inhibit uterine contractions and prolong pregnancy in women with preterm labor, not to prevent respiratory distress syndrome.

Choice D.Indomethacin is wrong because it is a nonsteroidal anti-inflammatory drug that is used to inhibit prostaglandin synthesis and reduce uterine activity in women with preterm labor, not to prevent respiratory distress syndrome.However, it can also cause premature closure of the ductus arteriosus in the fetus and should be avoided after 32 weeks of gestation.

Normal ranges for gestational age are 37 to 42 weeks.

Preterm labor is defined as regular uterine contractions with cervical changes.

Corticosteroids are given to pregnant women who are at risk of preterm labor to help mature the lungs of the fetus and reduce the risk of respiratory distress syndrome and other complications.Corticosteroids also have a protective effect on the brain and reduce the risk of bleeding and cerebral palsy.

Choice A is wrong because administering intravenous fluids is not a specific intervention to address possible outcomes and complications of preterm labor.Intravenous fluids may be given to correct dehydration or electrolyte imbalance, but they do not prevent or treat preterm labor.

Choice B is wrong because administering tocolytics is an intervention to delay preterm labor, not to address possible outcomes and complications.

Tocolytics are drugs that inhibit uterine contractions and prolong pregnancy for a short period of time, usually 24 to 48 hours, to allow for the administration of corticosteroids or the transfer of the mother to a facility with neonatal intensive care.