A nurse is educating a group of clients about the contraindications of warfarin therapy. Which of the following statements should the nurse include in the teaching?
"Clients who have glaucoma should not take warfarin."
"Clients who have rheumatoid arthritis should not take warfarin."
"Clients who are pregnant should not take warfarin."
"Clients who have hyperthyroidism should not take warfarin."
The Correct Answer is C
Warfarin is a coumarin anticoagulant that has potential to increase the risk of bleeding. When taken during pregnancy, warfarin causes fetal bleeding. Warfarin is also teratogenic and it causes various birth defects including skeletal abnormalities, hypoplastic nose, intellectual disabilities and deafness hence it's contraindicated. Pregnant women who require anticoagulation are put of heparin in the place of warfarin to prevent these complications.
A. B, D - are not contraindications for warfarin use.
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Correct Answer is C
Explanation
warfarin inhibits vitamin K epoxide reductase interfering with the synthesis of vitamin K dependent clotting factors (II, VII, IX, and X). This prolongs the prothrombin time, expressed in the form of INR international normalized ratio. Monitoring of INR helps to ensure that the prescribed dosages are within the therapeutic levels without increasing the risk of bleeding. The target INR range is between 2.5 and 3.5.
A. Used to monitor heparin therapy
B, D- not used for monitoring
Correct Answer is C
Explanation
Cyclobenzaprine is a muscle relaxant used to relieve muscle spasms in various musculoskeletal conditions. One of the common side effects of cyclobenzaprine is drowsiness and impaired cognitive function, which can affect the ability to operate machinery or drive safely.
A. Cyclobenzaprine is used to reduce muscle spasms, so monitoring for increased muscle spasms would not be appropriate.
B. Nausea can be a common side effect of cyclobenzaprine, but it does not typically require discontinuation of the medication unless it is severe or persistent and causing significant distress.
D. Cyclobenzaprine does not typically cause urine discoloration, so expecting urine to turn orange is not relevant to the medication.
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