A nurse is explaining myasthenia gravis to a family. Which of the following points would be included in the explanation? (Select All that Apply.)
Is it caused by demyelination of the nerve fibers.
Is it thought to be an autoimmune disease.
It is associated with destruction of acetylcholine receptor sites.
Once symptoms present, it has a 5-year survival rate.
It is a chronic and progressive muscular disease.
Is it best treated with antibiotics.
Correct Answer : B,C,E
A) Is it caused by demyelination of the nerve fibers:
Myasthenia gravis is not primarily caused by demyelination of nerve fibers. It is characterized by dysfunction at the neuromuscular junction, specifically involving the acetylcholine receptors.
B) Is it thought to be an autoimmune disease:
This is correct. Myasthenia gravis is considered an autoimmune disorder in which the body's immune system mistakenly targets and attacks its own tissues, particularly the acetylcholine receptors at the neuromuscular junction.
C) It is associated with destruction of acetylcholine receptor sites:
This is correct. In myasthenia gravis, there is a reduction in the number of functional acetylcholine receptors due to autoimmune-mediated destruction or blocking of these receptors.
D) Once symptoms present, it has a 5-year survival rate:
This statement is inaccurate. Myasthenia gravis is a chronic condition, but survival rates are not determined by the onset of symptoms. With appropriate treatment, many individuals with myasthenia gravis can manage their symptoms effectively and have a normal life expectancy.
E) It is a chronic and progressive muscular disease:
This is correct. Myasthenia gravis is a chronic neuromuscular disorder characterized by fluctuating muscle weakness and fatigue. While it is chronic, it is not necessarily progressive in all cases, as symptoms may stabilize or improve with treatment.
F) Is it best treated with antibiotics:
Antibiotics are not the primary treatment for myasthenia gravis. Treatment typically involves medications that enhance neuromuscular transmission, such as acetylcholinesterase inhibitors or immunosuppressive drugs, along with other supportive measures.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A) Take this medication with food:
Captopril is an ACE inhibitor, known to work best on an empty stomach. Food can reduce its absorption, impacting its effectiveness. Thus, while clients can take captopril with or without food, it's generally recommended to take it on an empty stomach for optimal results.
B) Monitor for a cough:
Captopril, an ACE inhibitor, commonly induces a persistent, dry cough due to the accumulation of bradykinin. This side effect can be bothersome and may necessitate discontinuation of the medication. Therefore, patients should be vigilant for the onset of a cough and promptly report it to their healthcare provider.
C) Avoid bananas:
Although captopril can occasionally lead to hyperkalemia, advising patients to avoid bananas specifically may not be necessary. While bananas are potassium-rich, restricting them alone might not significantly impact potassium levels. However, patients should be educated on monitoring potassium intake and informed of potential dietary modifications if hyperkalemia occurs.
D) Hold medication for heart rate less than 100/min:
Captopril is not known to directly affect heart rate. This instruction may be more applicable to medications like beta-blockers, which can lower heart rate as part of their mechanism of action. Therefore, holding captopril for heart rates below 100/min may not be clinically indicated.
Correct Answer is ["675"]
Explanation
1. Convert client weight from pounds to kilograms (kg):
We know 1 kg = 2.205 pounds.
Client weight (kg) = 198 lb / 2.205 lb/kg = 90 kg (round to nearest whole number for this calculation).
2. Calculate the total daily dosage:
Prescribed dosage per kg per day: 15 mg/kg/day
Client weight (kg): 90 kg (rounded value from step 1)
Total daily dosage (mg): Dosage (mg/kg/day) x Client weight (kg)
Total daily dosage (mg): 15 mg/kg/day x 90 kg = 1350 mg/day
3. Since the dosage is divided equally every 12 hours, calculate the amount per dose:
Frequency of administration: Every 12 hours
Total daily dosage (mg): 1350 mg/day
Dosage per dose (mg) = Total daily dosage (mg) / Frequency (doses/day)
Dosage per dose (mg) = 1350 mg/day / 2 doses/day
Dosage per dose (mg) = 675 mg/dose (round to nearest whole number as requested)
Therefore, the nurse should administer approximately 675 mg of vancomycin with each dose.
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