A nurse is planning to administer medications to a client who weighs 198 lb. The prescription reads, "filgrastim 5 mcg/kg, subcutaneous, daily." Available is filgrastim 300 mcg/mL. How many mL should the nurse plan to give with each dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Answer and Explanation

The Correct Answer is ["1.5"]

Convert the client's weight from pounds to kilograms by dividing by 2.2. 198 lb / 2.2 = 90 kg

Calculate the dose of filgrastim in micrograms by multiplying the client's weight in kilograms by the prescribed dose per kilogram. 90 kg x 5 mcg/kg = 450 mcg

Calculate the volume of filgrastim in milliliters by dividing the dose in micrograms by the concentration of the available solution. 450 mcg / 300 mcg/mL = 1.5 mL

Round the answer to the nearest tenth. The nurse should plan to give 1.5 mL of filgrastim with each dose.

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Correct Answer is C

Explanation

A. This statement is incorrect. While it’s essential not to exceed the recommended dose, the

maximum daily limit for nicotine gum is 24 pieces, not 40. Using more than the recommended amount can lead to adverse effects
B. This information is not accurate. Nicotine gum is typically used for a shorter duration. The

treatment plan varies, but it’s essential to follow the recommended dosing and gradually reduce usage over time. The goal is to quit smoking successfully, not to use the gum for 9 months
C. This advice is correct. Nicotine gum is not used like ordinary chewing gum. You should chew it a few times and then “park” it between your cheek and the space below your teeth. The nicotine is absorbed mostly in your mouth. Chewing it slowly over 30 minutes allows for
effective absorption and helps control withdrawal symptoms

D. Drinking water before chewing nicotine gum is not a necessary instruction for its use.

A. Oxycodone blocks the sodium channel suspending nerve conduction. B. Oxycodone inhibits prostaglandin synthesis. C. Oxycodone promotes vasodilation of cranial arteries. D. Oxycodone uses central nervous system depression.

Correct Answer is D

Explanation

A. Oxycodone primarily exerts its analgesic effects through binding to opioid receptors and modulating neurotransmitter release, rather than blocking sodium channels.
B. Oxycodone does not directly inhibit prostaglandin synthesis; this mechanism is associated with nonsteroidal anti-inflammatory drugs (NSAIDs).
C. Oxycodone does not promote vasodilation of cranial arteries. This mechanism is more commonly associated with medications used to treat migraines, such as triptans.
D. Oxycodone is an opioid analgesic that acts centrally on the nervous system to depress respiratory drive, leading to respiratory depression, especially at higher doses.

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Naxlex Comprehensive Predictor Exams

A nurse is providing teaching to a client who reports smoking 3 packs of cigarettes per day and has a prescription for nicotine gum. Which of the following instructions should the nurse include in the teaching?

Correct Answer is C

Explanation

A nurse is assessing a client who has received oxycodone. The nurse notes that the client's respiratory rate is 8/min. The nurse should identify that which of the following is the pathophysiology for the client's respiratory rate?

Correct Answer is D

Explanation

A nurse is assessing a client who is receiving a dose of IV amphotericin B. Which of the following findings should indicate to the nurse that the client is experiencing an acute infusion reaction?

A nurse is assessing the vital signs of a client who is taking amiodarone. The nurse should anticipate which of the following findings as an adverse effect of the medication?

A nurse is caring for a client who is receiving parenteral nutrition and identifies that the client has hyperkalemia. Which of the following actions should the nurse take?

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A nurse is providing teaching to a client who has a new prescription for theophylline, a sustained-release capsule. Which of the following statements by the client indicates an understanding of the teaching?

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