A nurse is preparing to administer erythromycin PO to a client who has an infection. The nurse checks the client's medical record and notes that the client has a severe allergy to penicillin. Which of the following actions should the nurse take?

A. Increased respiratory rate is a sign that naloxone is effectively reversing opioid-induced respiratory depression. Opioids can suppress the respiratory drive, leading to hypoventilation or respiratory arrest. Naloxone works by competitively binding to opioid receptors and displacing opioids, thereby restoring normal respiratory function.
B. Increased temperature is not a direct effect of naloxone administration. Naloxone primarily reverses the central nervous system depressant effects of opioids, including respiratory depression and sedation, rather than affecting body temperature.
C. Naloxone does not directly affect pain perception. Its primary action is to reverse the respiratory depression and central nervous system depression caused by opioids. While the client may experience pain relief indirectly as a result of improved respiratory function and consciousness, naloxone itself does not directly reduce pain.
D. Decreased blood pressure is not a direct effect of naloxone administration. Naloxone primarily reverses the respiratory and central nervous system depressant effects of opioids, rather than affecting blood pressure directly.

B. Weight gain can indicate that methimazole is effectively managing the thyroid imbalance. Methimazole is commonly used to treat hyperthyroidism by inhibiting the production of thyroid hormones. Weight gain may occur as a result of restoring thyroid hormone levels to normal, which can lead to a decrease in metabolism and an improvement in symptoms associated with hyperthyroidism, such as unintended weight loss.
A. Increased libido is not typically associated with the effectiveness of methimazole in treating thyroid imbalance. Thyroid dysfunction, whether hyperthyroidism or hypothyroidism, can affect libido, but improvement in libido would not specifically indicate the effectiveness of methimazole.
C. Decreased menstrual flow is not a typical indicator of the effectiveness of methimazole in treating thyroid imbalance. Thyroid dysfunction can affect menstrual cycles, with hyperthyroidism often associated with lighter or irregular menstrual periods. However, improvement in menstrual flow alone would not necessarily indicate the effectiveness of methimazole.
D. Clear breath sounds are not specific to the effectiveness of methimazole in treating thyroid imbalance. While methimazole can help manage symptoms of hyperthyroidism, such as palpitations and shortness of breath, clear breath sounds do not directly indicate thyroid function improvement.