A nurse is preparing to administer ivermectin to a client who has onchocerciasis (river blindness).
Which of the following adverse effects should the nurse monitor for in this client?

Hypertension

Tinnitus

Mazzotti reaction

Stevens-Johnson syndrome.

Answer and Explanation

The Correct Answer is C

A Mazzotti reaction is a severe inflammatory response that can occur after taking ivermectin for onchocerciasis (river blindness), a parasitic infection caused by Onchocerca volvulus. The reaction is due to the death of the microfilariae (larvae) of the parasite and can cause fever, rash, itching, joint pain, swollen lymph nodes, and eye inflammation.

Choice A is wrong because hypertension is not a common adverse effect of ivermectin. Hypotension, however, can occur in some cases.

Choice B is wrong because tinnitus is not a common adverse effect of ivermectin. Tinnitus is a ringing or buzzing sound in the ears that can be caused by various factors, such as exposure to loud noise, ear infections, or certain medications.

Choice D is wrong because Stevens-Johnson syndrome is not a common adverse effect of ivermectin.

Stevens-Johnson syndrome is a rare but serious skin reaction that can be triggered by infections or medications.

It causes blisters and peeling of the skin and mucous membranes.

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Correct Answer is A

Explanation

This is because itraconazole can cause renal impairment and decreased urine output as an adverse effect.A normal serum creatinine level is 0.6 to 1.2 mg/dL for males and 0.5 to 1.1 mg/dL for females.

Choice B is wrong because decreased serum potassium level is not an adverse effect of itraconazole.Itraconazole can cause hypokalemia, which is a low level of potassium in the blood, but this is usually due to fluid retention and heart failure caused by the drug.A normal serum potassium level is 3.5 to 5.0 mEq/L.

Choice C is wrong because increased serum glucose level is not an adverse effect of itraconazole.Itraconazole can cause hyperglycemia, which is a high level of glucose in the blood, but this is usually due to diabetes mellitus or steroid use in patients taking the drug.A normal serum glucose level is 70 to 100 mg/dL.

Choice D is wrong because decreased white blood cell count is not an adverse effect of itraconazole.Itraconazole can cause leukopenia, which is a low level of white blood cells in the blood, but this is usually due to bone marrow suppression or infection in patients taking the drug.A normal white blood cell count is 4,500 to 11,000 cells/mm3.

A. “I will report any changes in my vision to my doctor.” B. “I will avoid eating foods that contain tyramine.” C. “I will take this medication on an empty stomach.” D. “I will continue to take this medication until I feel better."

Correct Answer is D

Explanation

This statement indicates a need for further teaching because linezolid should be taken for the full prescribed course of treatment, even if the symptoms improve or resolve.Stopping the medication too soon can lead to bacterial resistance or recurrence of the infection.

Choice A is wrong because it is a correct statement.Linezolid can cause optic neuropathy or vision changes, so patients should report any changes in their vision to their doctor.

Choice B is wrong because it is a correct statement.

Linezolid can interact with foods that contain tyramine, such as cheese and red wine, and cause a hypertensive crisis.Patients should avoid eating foods that contain tyramine while taking linezolid and for two weeks after stopping the medication.

Choice C is wrong because it is a correct statement.Linezolid can be taken with or without food, but taking it on an empty stomach may help with absorption and effectiveness.

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A nurse is preparing to administer ivermectin to a client who has onchocerciasis (river blindness). Which of the following adverse effects should the nurse monitor for in this client?

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Naxlex Comprehensive Predictor Exams

A nurse is reviewing laboratory results for a client who has a fungal infection and is receiving itraconazole therapy. Which of the following findings should alert the nurse to a potential adverse effect of this medication?

Correct Answer is A

Explanation

The nurse is providing discharge teaching for a patient who will be taking oral linezolid (Zyvox) to treat a complicated skin infection caused by vancomycin-resistant enterococci (VRE). Which statement by the patient indicates a need for further teaching?

Correct Answer is D

Explanation

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A nurse is preparing to administer ivermectin to a client who has onchocerciasis (river blindness).
Which of the following adverse effects should the nurse monitor for in this client?