A nurse is preparing to administer ivermectin to a client who has onchocerciasis (river blindness).
Which of the following adverse effects should the nurse monitor for in this client?
Hypertension
Tinnitus
Mazzotti reaction
Stevens-Johnson syndrome.
The Correct Answer is C
A Mazzotti reaction is a severe inflammatory response that can occur after taking ivermectin for onchocerciasis (river blindness), a parasitic infection caused by Onchocerca volvulus. The reaction is due to the death of the microfilariae (larvae) of the parasite and can cause fever, rash, itching, joint pain, swollen lymph nodes, and eye inflammation.
Choice A is wrong because hypertension is not a common adverse effect of ivermectin. Hypotension, however, can occur in some cases.
Choice B is wrong because tinnitus is not a common adverse effect of ivermectin. Tinnitus is a ringing or buzzing sound in the ears that can be caused by various factors, such as exposure to loud noise, ear infections, or certain medications.
Choice D is wrong because Stevens-Johnson syndrome is not a common adverse effect of ivermectin.
Stevens-Johnson syndrome is a rare but serious skin reaction that can be triggered by infections or medications.
It causes blisters and peeling of the skin and mucous membranes.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["D","E"]
Explanation
A microbe acquires antibiotic resistance by transferring DNA coding to other bacteria or by spontaneous mutation in the microbial genome.
These genetic changes allow the microbe to survive the effects of the antibiotic and pass on the resistance to its offspring.
ChoiceAis wrong because the host does not develop medication resistance, but the microbe does.
ChoiceBis wrong because the minimum bactericidal concentration (MBC) is the lowest concentration of an antibiotic needed to kill 99.9% of bacteria, not a mechanism of resistance.
ChoiceCis wrong because incorrect dosing does not cause ribosome mutations, but may promote the emergence of drug-resistant microbes by exposing them to suboptimal levels of the antibiotic.
Correct Answer is ["A","B","C","E"]
Explanation
Cefazolin can cause serious or life-threatening allergic reactions in some patients, especially those with a history of penicillin allergy.The most common allergic reactions to cefazolin are immediate reactions, such as anaphylaxis, urticaria, bronchospasm, and angioedema.These reactions usually occur within one hour of the drug administration and may involve symptoms such as rash, itching, swelling, difficulty breathing, low blood pressure, and shock.Immediate reactions are mediated by immunoglobulin E (IgE) antibodies that bind to the drug and trigger the release of inflammatory mediators from mast cells and basophils.
Choice D is wrong because Stevens-Johnson syndrome is not a typical allergic reaction to cefazolin.
Stevens-Johnson syndrome is a rare and severe skin reaction that can be caused by various drugs, infections, or autoimmune diseases.
It involves blistering and peeling of the skin and mucous membranes, fever, malaise, and eye inflammation.
Stevens-Johnson syndrome is not mediated by IgE antibodies, but by other immune mechanisms that damage the skin cells.
Cefazolin is not known to cause Stevens-Johnson syndrome, although other cephalosporins have been reported to do so in rare cases.
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